Results 51 to 60 of about 94,361 (225)

Hepatocyte and keratinocyte growth factors and their receptors in human lung emphysema

BMC Pulmonary Medicine, 2005
Background Hepatocyte and keratinocyte growth factors are key growth factors in the process of alveolar repair. We hypothesized that excessive alveolar destruction observed in lung emphysema involves impaired expression of hepatocyte and keratinocyte ...
Marchal Joëlle, Leçon-Malas Véronique, Boutten Anne, Bonay Marcel, Soler Paul, Fournier Michel, Leseche Guy, Dehoux Monique, Crestani Bruno   +8 more
doaj   +1 more source

Oxymatrine Inhibits Epithelial‐Mesenchymal Transition to Alleviate Airway Remodeling in Chronic Obstructive Pulmonary Disease by Suppressing the TGF‐β1/Smad Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study explored the therapeutic efficacy of oxymatrine (OMT, C15H24N2O2) in a murine model of cigarette smoke (CS)‐induced chronic obstructive pulmonary disease (COPD) and elucidated its underlying mechanisms. A COPD model was established in mice through prolonged exposure to CS, followed by intraperitoneal administration of OMT (50 mg/kg)
Shuang Zhou, Ju‐Xiang Zhu, Jing Li
wiley   +1 more source

Higher body mass index is associated with increased lung stiffness and less airway obstruction in individuals with asthma and fixed airflow obstruction

ERJ Open Research, 2021
Sandra Rutting, David G. Chapman, Tanya Badal, Farid Sanai, Sabine C. Zimmermann, Cindy Thamrin, Gregory G. King, Katrina O. Tonga   +7 more
doaj   +1 more source

Potential Biomarkers for Disease Stratification and Prognosis Prediction in Pediatric Asthma: LCN2, sST2 and FGF21

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Pediatric asthma is a common chronic airway inflammatory disease, where accurate assessment of disease severity and prognosis prediction is crucial for treatment decisions. Currently, there is a lack of precise and effective biomarkers.
Xu Yang, Hai Wang, Yong‐Zheng Zhang, Yan‐Yan Chen, Xin‐Xin Xing, Yi‐Cheng Ding   +5 more
wiley   +1 more source

A formula for predicting emphysema extent in combined idiopathic pulmonary fibrosis and emphysema

Respiratory Research
Background No single pulmonary function test captures the functional effect of emphysema in idiopathic pulmonary fibrosis (IPF). Without experienced radiologists, other methods are needed to determine emphysema extent. Here, we report the development and
Athol U. Wells, Joseph Jacob, Nicola Sverzellati, Gary Cross, Joseph Barnett, Angelo De Lauretis, Katerina Antoniou, Derek Weycker, Mark Atwood, Klaus-Uwe Kirchgaessler, Vincent Cottin   +10 more
doaj   +1 more source

Characteristics of phenotypes of elderly patients with asthma

Allergology International, 2016
Background: The characteristics of phenotypes of elderly patients with asthma are unknown. The aim of this study was to classify these phenotypes using lung function tests and images from high-resolution computed tomography (HRCT), and to identify ...
Hiroyuki Sano, Takashi Iwanaga, Osamu Nishiyama, Akiko Sano, Yuji Higashimoto, Katsuyuki Tomita, Yuji Tohda   +6 more
doaj   +1 more source

Gastric emphysema [PDF]

Hong Kong Medical Journal, 2021
G, Liang, L C, Zeng, M G, Xie, M X, Zhang, Z H, Hou   +4 more
openaire   +2 more sources

Anterolateral‐Thigh Fascia Lata Free Flap Versus Fibula Free Flap for Mandibular Osteoradionecrosis

The Laryngoscope, EarlyView.
The anterolateral thigh fascia lata “rescue” free flap has been employed as a novel tool in the treatment of advanced partial thickness mandibular osteoradionecrosis. Compared with the traditional fibula free flap for the same indication, the “rescue” flap provides similar outcomes in terms of disease resolution, superior functional outcomes, and ...
Conrad K. Blunck, Alexander Havens, Michael A. Fritz, Brandon L. Prendes, Derek J. Vos, Amani Alvi, Sara Liu, Dane J. Genther, Peter J. Ciolek   +8 more
wiley   +1 more source

Perioperative Care for Pediatric Patients Undergoing Lung Surgery: Retrospective Single Center Review

Pediatric Anesthesia, EarlyView.
ABSTRACT Background Procedures involving lung surgery in the pediatric population are relatively uncommon and tend to be centralized in a limited number of institutions. Anesthesia literature is also sparse. Aims To have a clear overview of frequency, underlying pathologies, ICU and hospital stay, anesthetic techniques, one lung ventilation, and ...
Rianne P. Wauters, Andrea Baumert, Ignacio Malagon   +2 more
wiley   +1 more source

Role of Dual-Specificity Phosphatase 1 in Glucocorticoid-Driven Anti-inflammatory Responses

Frontiers in Immunology, 2019
Glucocorticoids (GCs) potently inhibit pro-inflammatory responses and are widely used for the treatment of inflammatory diseases, such as allergies, autoimmune disorders, and asthma. Dual-specificity phosphatase 1 (DUSP1), also known as mitogen-activated
Jessica Hoppstädter, Alaina J. Ammit, Alaina J. Ammit   +2 more
doaj   +1 more source