Results 81 to 90 of about 5,887,720 (272)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The influence of organizational characteristics of high-performing firms on work engagement and employee performance: the moderating role of age

Cogent Business & Management
This study examines how the organizational characteristics of high-performing firms influence employee work engagement and performance, with age as a moderating variable. The study used partial least squares structural equation modeling (PLS-SEM) to test
Jutamard Thaweepaiboonwong, Apinya Ingard, Jedsada Wongsansukcharoen, Panitada Limrueangrong   +3 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Individual Characteristics and Work Environment in an Effort to Encourage Improved Employee Performance at PT Siraj Badawi Cukup Rupiah

Indonesian Interdisciplinary Journal of Sharia Economics
This study focuses on individual characteristics and work environment to encourage increased employee performance at PT Siraj Badawi Cukup Rupiah, located in Cirebon Regency.
Abel Celani, Feby Amanda Putri, Noveria Susijawati   +2 more
doaj   +1 more source

Patterns of Employee Particpation and Industrial Democracy in UK ESOPs [PDF]

This paper examines the institutional characteristics of UK ESOPs and considers the extent to which ESOPs extend employee participation and industrial democracy. It is suggested that ESOPs in themselves do not extend industrial democracy.
J McDonald, N Wilson, A Robinson, A Pendleton   +3 more
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Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Pengaruh Lingkungan Kerja dan Karakteristik Individu Terhadap Kinerja Karyawan PT. Cassia Coop Sungai Penuh

Jurnal Benefita, 2019
The purpose of the research is to find out the Effect of Work Environment and Individual Characteristics on the Employee Performance of PT. Cassia Coop Sungai Penuh. The samples taken were 42 people who worked at PT Cassia Coop Sungai Penuh.
Mauledy Ahmad
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Office of Injured Employee Counsel Quarterly Review

, 2006
Quarterly newsletter discussing the activities of the Office of Injured Employee Counsel in ...
Texas. Office of Injured Employee Counsel.
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