Results 71 to 80 of about 5,887,720 (272)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Differences in employee overall job satisfaction between public and private sector organizations have long been a topic of organizational academic debate.
Lam D. Nguyen
doaj
This study aimed to investigate the contribution of job characteristics and job training to employee performance through the mediating role of work motivation. Data were collected through questionnaires with saturated sampling techniques.
Indanaa Luthfiani, Tristiana Rijanti
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Office of Injured Employee Counsel Quarterly Review
Quarterly newsletter discussing the activities of the Office of Injured Employee Counsel in ...
Texas. Office of Injured Employee Counsel.
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
The purpose of this study was to determine the effect of organizational communication, individual characteristics, work ability and work ethic on employee performance at PT. Nusantara Plantation IV.
Haya Fachira +2 more
doaj +1 more source
Employee engagement is an important issue that is the main concern of the organization's leaders in managing its employees. The changing characteristics of the employee generation are becoming a specific challenge for human resource management.
Elita Amrina +2 more
openaire +1 more source
Human resources are important factors that need to be considered by companies, with superior human resources, the company has the potential to achieve its goals effectively and efficiently. Besides that, the company can also win the competition and expand its business. This study aims to analyze the effect of employee characteristics and organizational
openaire +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source

