Results 51 to 60 of about 1,615,850 (271)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The role of creative engagement in competence and career development toward performance
Orientation: Creative engagement is the process of involving employees in creative activities of innovation, creativity and active participation in work. Competence and career development have an impact on employee performance.
Singgih Bektiarso, Sri W.L.H. Setyanti
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Employee participation is essential for the effectiveness of the organization. The employees mentioned are not only reliable but also loyal, committed, and willing to contribute better performance, or in other words, employees with employee engagement ...
Endah Mujiasih
doaj +1 more source
Background: Productivity of the South African work force remains an issue of central concern for business. It plays an important role in the life of every person and the performance of every business. Creating a working environment that encourages worker
Robert W.D. Zondo
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Employee engagement in Nigeria: The role of leaders and boundary variables
Orientation: Engaged employees make a valuable contribution to organisational agility and productivity in challenging business environments. Hence, identifying factors that enhance employee engagement is important in the Nigerian context.
Okechukwu E. Amah
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Employee engagement in a digital environment
Digital transformation is the process of integrating digital technology in all areas of the business to achieve its strategic goals. The focus of digital transformation projects often tends to be on the technology rather than on the human aspect.
Wöllenstein, Christian +2 more
core +1 more source
This study examines the impact of organizational culture on employee engagement and employee performance. Within the organization, organizational culture plays an important role in building employee engagement, and ultimately in Employee Performance. The
Halid Hasan +3 more
doaj

