Results 91 to 100 of about 168,775 (312)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Management of Employees’ Performance Culture

open access: yesInternational Journal of Economics and Business Administration, 2019
Purpose: The aim of this article is to evaluate the development of the employees' competence as human capital in Aloei Saboe Gorontalo hospital. Design/Methodology/Approach: The research was conducted in the local hospital Prof. Dr. H. Aloei Saboe Gorontalo, located around Tomini gulf.
openaire   +3 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The Relationships among Employee Satisfaction, Productivity, Performance and Customer Satisfaction [PDF]

open access: yes
Today, the linkage between employee satisfaction and customer satisfaction, productivity, and performance is undeniable, based on numerous studies that support the correlation.
Hanan Abd EL MONIEM   +1 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

The Impact of mobile communication on employee performance

open access: yes, 2006
A dissertation submitted to the Department of Computer and Engineering for the MBAABSTRACT In the current competitive environment, the need for better management of all organizational resources, specifically human resource management has become a ...
Kumara, GDPA
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

High Performance Work Practices and Employee Voice: A Comparison of Japanese and Korean Workers [PDF]

open access: yes
Using a unique new cross-national survey of Japanese and Korean workers, we report the first systematic evidence on the effects on employee voice of High Performance Work Practices (HPWPs) from the two economies which are noted for the wide use of HPWPs.
Chuma, Hiroyuki   +4 more
core  

The Decision Support System Design Of Employee Performance Appraisal Using Analytical Hierarchi Process (AHP) Method [PDF]

open access: yes, 2012
A performance appraisal is important for every employee and it is also useful for companies to assign the next policy action. In RS Roemani, the performance appraisal process is used for the promotion, the performance evaluation, the hajj subsidy, the ...
Rochmat , Taufiq
core  

High-Performance Work System and Employee Work Performance: A Moderated Mediation Model of Ambidextrous Leadership and Employee Ambidexterity

open access: yesInternational Journal of Business Science and Applied Management, 2023
The purpose of this study is to explore a moderated mediation model of ambidextrous leadership and employee ambidexterity in the relationship between a high-performance work system and employee work performance.
Ijigu, A.W., Alemu, A.E., & Kuhil, A.M.
doaj  

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