Results 91 to 100 of about 8,776,584 (297)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
High commitment performance management: the roles of justice and trust [PDF]
, 2011 Purpose – The purpose of this paper is to explore the relationship between employees' perceptions of a particular subsystem of HRM practices (performance management) and their commitment to the organisation. In addition, the study seeks to examine the
Farndale, Elaine +9 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
International Journal of Business Science and Applied Management, 2023 The purpose of this study is to explore a moderated mediation model of ambidextrous leadership and employee ambidexterity in the relationship between a high-performance work system and employee work performance.
Ijigu, A.W., Alemu, A.E., & Kuhil, A.M.
doaj
Effect of Employee Independence on Employee Performance
International Journal of Engineering, Business and Management, 2022 Jacqueline Tingo, Samwel Mseti
openaire +1 more source
Relationship between employee aspects and employee performance
Journal of Management, 2015 Studies found that employee performance is affected by employee aspects such as reward systems, job satisfaction and organizational commitment. However, the relationships among these have not been proved clearly. Thus, this study is attempted to know about the relationship between employee aspects and employee reward.
Ismail, M. B. M. +2 more
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The Impact of mobile communication on employee performance
, 2006 A dissertation submitted to the Department of Computer and Engineering for the MBAABSTRACT In the current competitive environment, the need for better management of all organizational resources, specifically human resource management has become a ...
Kumara, GDPA
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source