Results 121 to 130 of about 1,082,560 (364)
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Impact of Toxic Leadership on Employee Performance. [PDF]
Health Psychol Res, 2022 Wolor CW +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Performance management system and its role for employee performance: Evidence from Ethiopian SMEs. [PDF]
Heliyon, 2023 Siraj N, Hágen I.
europepmc +1 more source
PENGARUH MOTIVASI KERJA TERHADAP KINERJA KARYAWAN [PDF]
The labor conditions in Indonesia are confronted with issues of unemployment, low productivity, and a significant number of workers employed in the informal sector. Low productivity impacts the level of employee performance. Performance becomes a crucial
Hasanah, Ambar Dyna
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Work stress, mental health, and employee performance. [PDF]
Front Psychol, 2022 Chen B, Wang L, Li B, Liu W.
europepmc +1 more source
Impact of stressors on the performance of employees [PDF]
It is important to recognize workplace stress because workplace stressors badly affect people’s mental as well as physiological health. Some of the reasons of stress at workplace could be the inability to meet out the demands of the job, relationship ...
Munir, Kashif, Rana, Badar-ul-islam
core +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source