Results 131 to 140 of about 380,937 (381)

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

Employee Performance Management: Implementation of Assessment System to Improve Organizational Effectiveness

open access: yesIndonesian Interdisciplinary Journal of Sharia Economics
This study aims to analyze the implementation of the employee performance appraisal system in the roof tile industry in Majalengka Regency, with a focus on identifying factors that influence the effectiveness of the performance appraisal system and its ...
Siswayu Gamar Maulida   +2 more
doaj   +1 more source

IMPLEMENTASI IMPORTANCE AND PERFORMANCE ANALYSIS (IPA) DALAM PELAKSANAAN PENILAIAN KINERJA KARYAWAN (PNS) (Studi pada Kementerian Pekerjaan Umum Dan Perumahan Rakyat, SNVT PJPA Pemali-Juana PPK PAT dan PPK PAB) [PDF]

open access: yes, 2017
This study aims to examine the implementation of performance appraisal at the Ministry of Public Works and Public Housing, SNVT PJPA Pemali-Juana PPK PAT and PPK PAB.
NUGRAHA, Nur Chaida, YUNIAWAN , Ahyar
core  

A PASport to Service Quality

open access: yes, 2005
Part 1 of this article discussed the current service quality environment in which academic libraries find themselves operating, and the challenge for staff performance assessment as an integral element of maintaining and improving effective service ...
Brock, Lynn A.
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Audit Manajemen Untuk Menilai Kinerja Fungsi SDM (Studi Pada Fungsi Rekrutmen-seleksi-orientasi, Pelatihan Dan Pengembangan, Penilaian Prestasi Kerja, Dan Pemutusan Hubungan Kerja PT. Xyz Indonesia – Medan) [PDF]

open access: yes, 2016
This research aims to explain the performance of HR function through the implementation of management audit at the human resource department of PT. XYZ Indonesia – Medan which include the functions of recruitment-selection-orientation, learning and ...
Nasution, Y. P. (Yolanda)   +1 more
core  

SO, DID YOU DEVELOP YOUR COMPETENCE? The influence of performance appraisals on employees’ competence development [PDF]

open access: yes, 2012
This study focuses on the qualitative aspect of employee’s competence development that is of critical importance to both employee and organizational development.
Wenestam, Codine
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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