Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
"It Is Comparison That Makes People Miserable": Enterprise Social Media Visibility, Social Comparison Orientation, and Workplace Impostor Thoughts. [PDF]
So C, Zhou Y, Du J.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
PROTOCOL: Multisource Feedback and Work Performance: A Systematic Review and Meta-analysis. [PDF]
Wietrak E +3 more
europepmc +1 more source
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
The value management cycle as a sustainable HRM framework: insights from Chinese Huawei's practices of value creation, evaluation, and distribution. [PDF]
Liang R.
europepmc +1 more source
Impact of performance appraisal on employees’ motivation
Esta pesquisa tem como objetivo compreender as causas da motivação dos trabalhadores no processo de avaliação de desempenho. Colocou-se a hipótese de que uma maior perceção dos elementos constitutivos da avaliação de desempenho (exatidão percebida, satisfação com a avaliação, justiça processual, interacional, e distributiva) levaria a um maior nível de
openaire +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Personality, capability, and context: a 30 year integrative review and theoretical expansion of the Big Five framework. [PDF]
Alnafisah A.
europepmc +1 more source

