Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Safeguarding Well-Being Under Exploitative Leaders: The Buffering Effects of Follower Strategies on Perceived Injustice. [PDF]
Stress HealthBajaba S, Basaad S.
europepmc +1 more source
Impact of performance appraisal on employees’ motivation
, 2015 Esta pesquisa tem como objetivo compreender as causas da motivação dos trabalhadores no processo de avaliação de desempenho. Colocou-se a hipótese de que uma maior perceção dos elementos constitutivos da avaliação de desempenho (exatidão percebida, satisfação com a avaliação, justiça processual, interacional, e distributiva) levaria a um maior nível de
openaire +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
The Influence of Competent Managers on Employee Retention, Job Satisfaction and Well-Being in the Healthcare Industry - A Scoping Review. [PDF]
J Healthc LeadershKumar S, Fong BYF, Liang Z.
europepmc +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
A validity and reliability study of the performance appraisal motivation scale in a Turkish sample. [PDF]
BMC NursPolat Ş, Eskici GT, Şen HT.
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
"They Care a Lot": A Qualitative Study of Nurses' Perspective on the Performance Appraisal Process in Israel. [PDF]
J Nurs ManagRabenu E, Shertzer Y.
europepmc +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source