Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
From Synergy to Strain: Exploring the Psychological Mechanisms Linking Employee-AI Collaboration and Knowledge Hiding. [PDF]
Behav Sci (Basel)Li YB, Liao TH, Tsai CH, Wu TJ.
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Impact of performance appraisal on employees’ motivation
, 2015 Esta pesquisa tem como objetivo compreender as causas da motivação dos trabalhadores no processo de avaliação de desempenho. Colocou-se a hipótese de que uma maior perceção dos elementos constitutivos da avaliação de desempenho (exatidão percebida, satisfação com a avaliação, justiça processual, interacional, e distributiva) levaria a um maior nível de
openaire +1 more source
The value management cycle as a sustainable HRM framework: insights from Chinese Huawei's practices of value creation, evaluation, and distribution. [PDF]
Front PsycholLiang R.
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Personality, capability, and context: a 30 year integrative review and theoretical expansion of the Big Five framework. [PDF]
Front PsycholAlnafisah A.
europepmc +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
When resilience backfires: the counterintuitive effect of employee resilience in high-tech surveillance environments. [PDF]
Front PsycholChu J, Chu H.
europepmc +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source