Results 161 to 170 of about 380,937 (381)
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Effects of Dyadic Quality and Duration on Performance Appraisal
Performance evaluation is one of the fundamental tasks that have to be accomplished by an organization. It is a process through which the employee’s performance is evaluated and on the basis of which different decisions are taken.
Ayesha Amanullah Khan, Syed Tahir Hijazi
doaj
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
DEVELOPMENT OF THE ODOO SYSTEM FOR THE EMPLOYEE PERFORMANCE APPRAISAL SYSTEM IN HRM MODULE
In organizations, such as companies, performance evaluation aims to assess, motivate, and improve employee performance. Human resource development is achieved by recognizing employees' potential.
Reizki Jihan Melani +2 more
doaj +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Performance Appraisal-A Documentation and Evaluation of Employees [PDF]
Almas Sabir
openalex +1 more source
Perceived Impact of Performance Appraisal on Employee’s performance
This study explores the perceived impact of performance appraisal on employee performance at Vocation Investments and Securities, a leading financial services firm. Performance appraisal is a critical aspect of organizational management, aiming to assess and enhance employee performance. The study adopts a mixed-methods approach, combining quantitative
openaire +2 more sources
A Study on the Impact of Employee Performance Appraisal on Employee Satisfaction and Loyalty
Yuchi Mo
openalex +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source

