Results 71 to 80 of about 6,368 (261)

Exploring the mediating role of appraisal fairness between the relationship of ethical behaviour and employee performance: moderating role of organisational culture

open access: yesDiscover Sustainability
Employee performance remains a critical concern for organisations, particularly when undermined by unethical behaviour and unsupportive cultural environments.
Musa Muhammad   +7 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Digitalization of Employee Performance Appraisal System: Ensuring Fairness and Transparency in Human Resource (HR) Practices in Steel Construction Company

open access: yesJournal the Winners
Digital transformation in human resource department (HRD) within performance appraisal process is initiated from employee management and supported by the commitment of leaders to create aspects of openness and fairness. In this context, PT.
Alexander Wirapraja   +2 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Current state of the employee performance appraisal system in agricultural organizations in the Czech Republic

open access: yesActa Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2013
Employee performance appraisal is one of the most important human resource management tools. The first part of the article concentrates on the theoretical background. The second part evaluates the results of the quantitative survey.
Kateřina Venclová   +2 more
doaj   +1 more source

PERFORMANCE APPRAISAL OF EMPLOYEES

open access: yes
Performance appraisal helps to measure the strengths and weaknesses of employees. Theperception of employees towards performance appraisal systems had been described in thispaper. It is observed from this study that performance motivates employees and it providesfeedback on their capabilities.
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Effectiveness of The Performance Appraisal System of Functional Officials With Employee Work Targets at The Health Department of Southeast Sulawesi Province

open access: yesPublic Health of Indonesia
Background: The Employee Performance Objectives system represents a major reform in Indonesia’s civil service appraisal mechanism, yet its effectiveness depends on regulatory understanding, digital literacy, and evaluator competence.
Sartini Risky   +4 more
doaj   +1 more source

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