Results 121 to 130 of about 1,588,043 (289)
Cunningham Children's Home Supported Education and Employment for Older Youth in Care [PDF]
A collaboration of the University of Illinois School of Social Work/Children and Family Research Center and Cunningham Children's Home, the research described in this report analyzes empirically the status of Cunningham's existing vocational programming ...
Barry Ackerson +3 more
core
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Reducing gender inequalities to create a sustainable care system [PDF]
Women mainly provide family care, but as women’s economic opportunities increase they will not continue to bear the costs of providing care unaided. To create a sustainable care system, care and carers must be better supported and more highly valued to ...
Himmelweit, Susan, Land, Hilary
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
A qualitative study of the IPS employment specialist role in the context of Nav employment in Norway
Background Employment is recognised as a fundamental human right. Still, many people experiencing severe mental illness are outside the workforce. Appropriate employment has several benefits for mental health and is central to recovery and citizenship ...
Cathrine Moe +8 more
doaj +1 more source
Where is full employment? [PDF]
Unemployment in Australia is now at its lowest in over 30 years. This experience of low rates of unemployment has prompted a number of statements that the Australian economy is at or very close to full employment. However, even though unemployment is low
Mcdonald, Ian Martin
core +1 more source
Career learning journeys of Derby and Derbyshire NEETs [PDF]
Young people (aged under 25 years) typically represent a third of all unemployed people across Derby and Derbyshire. The numbers of young people aged between 16 and 18 years old who are either not in education, employment or training (known as NEETs) in ...
Hutchinson, Jo +2 more
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Beyond Piecework: Employment for Persons with Intellectual and Developmental Disabilities [PDF]
All people deserve competitive, fulfilling employment (Lysaght, Cobigo, Hamilton, 2011). Many people with intellectual or developmental disabilities (I/DD) have difficulty obtaining competitive employment despite desiring to work (Lysaght, Ouellett-Kuntz,
Brandwene, Kelly +4 more
core +1 more source

