Results 121 to 130 of about 1,592,470 (309)
Nordic Journal of Working Life StudiesSupported employment (SE) is increasingly implemented in employment services worldwide. The disruptive character of SE, involving a shift from ‘train-place’ to ‘place-train’ models of vocational rehabilitation, has led to growing recognition of ...
Blanka Støren-Vaczy, Vidar Bakkeli
doaj +1 more source
Who writes the pay slip? Do R&D subsidies merely increase researcher wages?. [PDF]
Government intervention in private R&D activity is common practice nowadays. However, its impact may not be unambiguously positive. First, companies may simply replace private R&D budgets with the public R&D grant.
Aerts, Kris
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
A qualitative study of the IPS employment specialist role in the context of Nav employment in Norway
BMC PsychiatryBackground Employment is recognised as a fundamental human right. Still, many people experiencing severe mental illness are outside the workforce. Appropriate employment has several benefits for mental health and is central to recovery and citizenship ...
Cathrine Moe +8 more
doaj +1 more source
Mentoring Programmes as a successful instrument for career development of people with disabilities and disadvantaged [PDF]
, 2007 [Excerpt] For many years the Mentoring, as a form of support for young people without work experience, is well-known practice. In the past ten years the Mentoring has proved itself as a wide-applied method of support in the career of people with ...
Leonardo da Vinci Pilot Projects
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Assessing Market-Based Solutions: Lessons from Evaluating a Youth Employment Initiative [PDF]
, 2016 Over the last few years, The Rockefeller Foundation – working with other funders, industry associations, governments and networks – has supported a portfolio of grantees to test a range of models for training, employing, and supporting low-income youth ...
Edward T. Jackson, Karim Harji
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
The Effects of Minimum Wages on Employment: Theory and Evidence from the US [PDF]
Recent work on the economic effects of minimum wages has stressed that the standard economic model, where increases in minimum wages depress employment, is not supported by the empirical findings in some labour markets.
Alan Manning +2 more
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Reducing gender inequalities to create a sustainable care system [PDF]
, 2008 Women mainly provide family care, but as women’s economic opportunities increase they will not continue to bear the costs of providing care unaided. To create a sustainable care system, care and carers must be better supported and more highly valued to ...
Himmelweit, Susan, Land, Hilary
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