Results 111 to 120 of about 75,325 (204)

Predicting enantiomer migration order of levobunolol via sequential computational modeling. [PDF]

J Mol Model
Maia PP, Freitas RMD, Guimarães L, Nascimento CS.   +3 more
europepmc   +1 more source

Temperature interacts with jack pine host defences to influence the growth of mountain pine beetle‐associated fungi

Agricultural and Forest Entomology, EarlyView.
Optimal growing temperatures varied with mountain pine beetle‐associated fungal species. There was only a marginal impact of temperature on the response of fungi to defensive monoterpenes of novel host pine. Interspecific facilitation occurred for Leptiographuim longiclavatum when grown in Ophiostoma montium‐induced treatments at optimal temperatures ...
Adrienne C. Bailey, Jennifer G. Klutsch, Kaitlyn Carey, Laureen F. I. Echiverri, Leah Flaherty   +4 more
wiley   +1 more source

Nadifloxacin: Multimilligram Enantioresolution and Enantioselective Ecotoxicological Studies. [PDF]

Chirality
Oliveira IE, Pereira D, Carvalho AR, Vidal R, da Silva Cabral L, Martorano LH, Junior FMS, Ribeiro C, Ribeiro ARL, Tiritan ME.   +9 more
europepmc   +1 more source

Enantiomer separation by CEC - Enantiomer separation by packed-capillary electrochromatography

, 1999
Three chiral compounds were successfully separated in a shea time with two enantiomer separation models on packed-capillary electrochromatograpy ( CEC). (i) 75 mu m I.D.
Zou, HF, Shi, W, Rui, JZ, Ni, JY, Zhang, YK, Zhu, J   +5 more
core  

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Protein-Based High-Performance Liquid Chromatography and Cyclodextrin-Capillary Electrokinetic Chromatography for the Chiral Separation of Azoles. [PDF]

Electrophoresis
Moreau S, Dillon A, Russo G, Wiedmer SK.
europepmc   +1 more source

Selective excitatory effects of γ‐glutamyl‐glycine, a glutathione metabolite, on GluN1 NMDA and mGlu5 receptors impacting synaptic plasticity

British Journal of Pharmacology, EarlyView.
Background and Purpose Gamma‐glutamyl dipeptides are essentially produced after glutathione (GSH) degradation. While several γ‐glutamyl dipeptides have been detected in different organs and body fluids, their biological activity remains elusive. This is the case for γ‐Glutamyl‐Glycine (γ‐Glu‐Gly) which has been found in different brain areas.
Sandro Andreu, Victoria Gizzi, Ugo Pasco, Fatiha Sebih, Yattou Zitouni, Pablo Jimenez, Valérie Rolland, Alain Chavanieu, Sébastien Estaran, Matthieu Rousset, Thierry Cens, Guillaume Cazals, Pierre Charnet, Janique Guiramand, Catherine Cohen‐Solal, Claudine Ménard, Marie‐Céleste de Jésus Ferreira, Nathalie Chevallier, Sonia Cantel, Michel Vignes, Julien Roussel   +20 more
wiley   +1 more source

Asymmetric Hydroamination Using Oxidative Radical Initiation in Flavin Enzymes. [PDF]

J Am Chem Soc
Brown AC, Del Angel Aguilar CE, Raps FC, Riehl PS, Hyster TK.   +4 more
europepmc   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

International Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

A Design of Experiments-Based Chiral HPLC Method for the Quantification of Talazoparib and Enantiomeric Purity Determination in Pharmaceutical Formulations. [PDF]

Chirality
Atila Karaca S, Aliyeva S, Yeniceli D.
europepmc   +1 more source