Results 121 to 130 of about 75,325 (204)

Pursuing patents for their own sake: How the investment discourse shapes patent quality and quantity

The Journal of World Intellectual Property, EarlyView.
Abstract Patent systems worldwide face criticisms over declining patent quality and increasing patent quantity. While most research focuses on strengthening examination rigour, this article turns attention to relatively underexplored patenting incentives.
Li Liu
wiley   +1 more source

Rethinking Chiral Decision-Making in Pharmaceutical Analysis: The Emerging Role of Artificial Intelligence. [PDF]

Chirality
Thanikachalam S, Kannappan V.
europepmc   +1 more source

Probing the molecular determinants of emission enhancement in RNA aptamer–metal complex systems

Photochemistry and Photobiology, EarlyView.
Light up aptamer: fluorophore pairs are widely used in sensing and imaging, with coordination complex fluorophores providing specific benefits due to their long‐lived emission. Here, we examined key structural and electronic features of these metal complexes to identify the requirements for productive engagement with an RNA aptamer.
Sarah M. Kriger, Joseph Spiconardi, Nathan Ennist, Edith C. Glazer   +3 more
wiley   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods. [PDF]

Chirality
Karayavuz B, Kirmizioglu CK.
europepmc   +1 more source

Post-Crosslinked Hydrazidine-Functionalized Resorcinol-Formaldehyde Imprinted Polymer for Selective S-Ketorolac Recognition. [PDF]

Chirality
Alnoman RB.
europepmc   +1 more source

Dose–response modelling uncovers compound‐specific inhibitory effects of host defence volatiles on mountain pine beetle fungal symbionts

Pest Management Science, Volume 82, Issue 10, Page 10241-10250, October 2026.
Host defence volatiles inhibit mountain pine beetle fungal symbionts in a compound‐ and enantiomer‐specific manner, with distinct dose–response profiles that reveal the multitarget chemical defences of beetle–fungi symbiotes. Abstract BACKGROUND The mountain pine beetle relies on symbiotic fungi to overcome host tree defences, yet these fungi must ...
Duo Zhang, Yanzhuo Liu, Xinyi Zhao, Guncha Ishangulyyeva, Nadir Erbilgin   +4 more
wiley   +1 more source

Enantioselective Determination of Carnitine Enantiomers in Food and Supplement Samples by Chiral Liquid Chromatography-Tandem Mass Spectrometry. [PDF]

Mass Spectrom (Tokyo)
Furusho A, Nakayama Y, Mizuno H, Sugiyama E, Kojima K, Todoroki K.   +5 more
europepmc   +1 more source

Supramolecular Behaviour of Heterochiral Dipeptides With Ile

Journal of Peptide Science, Volume 32, Issue 10, October 2026.
This study describes the supramolecular behaviour and gelation of heterochiral, aliphatic dipeptides d‐Ile‐l‐Xaa (Xaa = Ala, Val, Leu or Ile) in various solvents and buffered water at neutral pH. Metastable gels rapidly crystallised. X‐ray diffraction analysis was conducted to unveil the dipeptides' packing modes in amphipathic layers.
Erica Scarel, Paola Alletto, Simone Adorinni, Fabio Fazio, Giovanni Pierri, Consiglia Tedesco, Silvia Marchesan   +6 more
wiley   +1 more source

Enantioseparation of Chiral Compounds From Traditional Chinese Medicines on a Chiral Packed Capillary Column With UV Detection. [PDF]

Electrophoresis
Hu S, Hu X, Chen K, Liu Y, Deng Y, Yu L, Huang L.   +6 more
europepmc   +1 more source

Cannabinoid CB1 allosteric ligands suppress inflammatory pain in male mice without tolerance, motor impairment, memory deficits or respiratory depression

British Journal of Pharmacology, Volume 183, Issue 20, Page 6132-6153, October 2026.
Abstract Background and Purpose Positive allosteric modulators (PAMs) engage sites distinct from the orthosteric CB1 cannabinoid receptor binding site. GAT211, a racemic ligand, contains GAT228 (R) and GAT229 (S) enantiomers. Whether enantiomer‐mediated differences in allosteric activation or positive allosteric modulation translate into differences in
Ifeoluwa D. Solomon, Sumanta Garai, Ganesh A. Thakur, Andrea G. Hohmann   +3 more
wiley   +1 more source