Results 101 to 110 of about 75,325 (204)

Preserving Hierarchical Integrity During Primary Structure Modification of Spherulitic MOFs

Small, EarlyView.
A MOF‐74‐type zinc framework self‐organizes into well‐defined spherulitic superstructures while allowing precise covalent post‐synthetic modification (PSM) of the linkers. A built‐in tetrazine enables fast inverse electron‐demand Diels–Alder (iEDDA) functionalization to uniformly install primary amines.
Gabriela Kowacz, Damian Jędrzejowski, Dariusz Matoga   +2 more
wiley   +1 more source

Chiral HPLC Separation of Phosphonothrixin and Phosphonate Derivatives and Electronic Circular Dichroism Characterization of the Isolated Enantiomers. [PDF]

Electrophoresis
Maalouf M, Knab M, Gessner L, Engelhardt M, Friedrich S, Gross H, Boeckler F, Hughes CC, Lämmerhofer M.   +8 more
europepmc   +1 more source

Synthesis of Chiral Gold Nanostructures on Gold‐Coral‐Coated Transparent Conductive Oxide Substrates via [AuCl4]– and Cysteine Interactions for Enhanced Chiral Sensing

Small, EarlyView.
We developed hierarchical chiral Au nanostructures on Au coral structures on transparent conductive oxide substrates using only electrochemical methods. By controlling the interaction between [AuCl4]– and cysteine, we successfully tuned the morphology and circular dichroism of the resulting Au nanostructures.
Kenta Nakagawa, Junhe Wang, Tianji Zhang, Yuta Shiga, Olga Guselnikova, Takuya Nakanishi, Yusuke Yamauchi, Toru Asahi   +7 more
wiley   +1 more source

Integrated 1D-LC-HRMS and Heart-Cutting 2D-LC-MS for Impurity Profiling and Chiral Separation of Mitiglinide Drug Substance. [PDF]

Rapid Commun Mass Spectrom
Wang C, Zhou S, Sun W, Pan Y, Feng H.
europepmc   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Green Chiral HPLC Method for Lumefantrine Analysis: Method Development, Greenness Assessment, and Computational Studies. [PDF]

Chirality
Mohr A, das Neves GM, Segala É, Eifler-Lima VL, Steppe M.   +4 more
europepmc   +1 more source

Enhancing Chiroptical Selectivity and Device Stability of Chiral Perovskite Photodetectors Via Interfacial AlF3 Passivation

Small Methods, EarlyView.
An ALD‐grown AlF3 underlayer promotes grain growth, defect passivation, and improved crystalline ordering in chiral perovskite films. The resulting films exhibit enhanced chiroptical properties, superior circularly polarized light photodetector performance, and improved stability, establishing an inorganic interface‐engineering strategy broadly ...
Hyejin Lim, Su Hye Jeong, Chae Bin Lee, Yousang Won, Seungwon Lee, Inho Song, Wooseok Song, Ki‐Seok An, Sungwoong Park, Seungju Lee, Soonmin Yim, Yoon Ho Lee, Saewon Kang   +12 more
wiley   +1 more source

AQbD-Guided Chiral HPLC for Enantiomeric Impurity Analysis of Suzetrigine. [PDF]

Chirality
Alhunayhin SMN, Algohary AM, Althobaiti SA, Alluhayb AH, Shahin MI, Ibrahim AM, Hasanin THA.   +6 more
europepmc   +1 more source

A [ 18F]fluoroetil-tirozin tartalmú radiogyógyszer enantiomer tisztaságának vizsgálata UPLC eljárással

A [18F]fluoroetil-tirozin tartalmú radiogyógyszer enantiomer tisztaságának vizsgálatára egy új UPLC eljárás került kidolgozásra. A vizsgálathoz Waters BEH C18 50x2,1 mm, 1,7 um fordított fázisú állófázist alkalmaztunk, amelyen sikeresen elválasztható az ...
Csonka, Viktória
core  

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source