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Enantiomers

open access: yes, 2021
International audienceOnly in exceptional cases, a pair of enantiomers do form a series of mixed crystals. The most well-known of the exceptions is the system laevorotatory carvoxime+dextrorotatory carvoxime; its properties are discussed in some detail ...
I. B. Rietveld   +3 more
core   +2 more sources

Copper (II) Ions Induced Self-Disproportionation of Enantiomers in Capillary Electrophoresis for the Quantification of Atenolol Enantiomers

open access: yesMolecules, 2023
Despite the fact that the self-disproportionation of enantiomers (SDE) has been found for several decades and has been widely used in crystallization, sublimation and chromatography for the purification or separation of nonracemic compounds, the ...
Shaoqiang Hu
doaj   +2 more sources

Enantiomers and Their Resolution [PDF]

open access: yesEncyclopedia, 2022
Enantiomers share the same chemical formula but have different chemical structures, i.e., type of isomers. Enantiomers are present in several drugs, perfumes, food, and are a fundamental part of biomolecules.
Karen V. Pontes   +2 more
core   +3 more sources

Stereoselectivity of In Vivo Processes and Bioactivity of Farrerol Enantiomers

open access: yesMolecules
Farrerol, a bioactive compound found in Folium Rhododendri daurici, demonstrates various biological and pharmacological effects. Nevertheless, the stereoselectivity of in vivo processes and bioactivity between its enantiomers have not been thoroughly ...
Lirong Chen   +6 more
doaj   +2 more sources

Chiral drugs - a standard or a challenge for modern pharmacy? Considerations on selected derivatives of 2-arylpropionic acid. [PDF]

open access: yesFarmacja Polska, 2022
: The US Food and Drug Administration (FDA) stated in 1992, which drew attention to the importance of chiral drugs. Enantiomers, which are optical isomers of a molecule with a stereogenic center, most often have different pharmacological and ...
Natalia Kocot   +4 more
doaj   +1 more source

Asymmetric Total Syntheses of Both Enantiomers of Plymuthipyranone B and Its Unnatural Analogues: Evaluation of anti-MRSA Activity and Its Chiral Discrimination

open access: yesPharmaceuticals, 2021
Chiral total syntheses of both enantiomers of the anti-MRSA active plymuthipyranone B and all of the both enantiomers of three unnatural and synthetic analogues were performed.
Mizuki Moriyama   +4 more
doaj   +1 more source

Enantioselective Interactions of Anti-Infective 8-Aminoquinoline Therapeutics with Human Monoamine Oxidases A and B

open access: yesPharmaceuticals, 2021
8-Aminoquinolines (8-AQs) are an important class of anti-infective therapeutics. The monoamine oxidases (MAOs) play a key role in metabolism of 8-AQs. A major role for MAO-A in metabolism of primaquine (PQ), the prototypical 8-AQ antimalarial, has been ...
Narayan D. Chaurasiya   +5 more
doaj   +1 more source

Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods

open access: yesMolecules, 2021
Enzymes, receptors, and other binding molecules in biological processes can recognize enantiomers as different molecular entities, due to their different dissociation constants, leading to diverse responses in biological processes. Enantioselectivity can
Maria Miguel Coelho   +3 more
doaj   +1 more source

Chiral Flavonoids as Antitumor Agents

open access: yesPharmaceuticals, 2021
Flavonoids are a group of natural products with a great structural diversity, widely distributed in plant kingdom. They play an important role in plant growth, development and defense against aggressors.
Cláudia Pinto   +3 more
doaj   +1 more source

Natural Enantiomers: Occurrence, Biogenesis and Biological Properties

open access: yesMolecules, 2022
The knowledge that natural products (NPs) are potent and selective modulators of important biomacromolecules (e.g., DNA and proteins) has inspired some of the world’s most successful pharmaceuticals and agrochemicals.
Jin-Hai Yu   +3 more
doaj   +1 more source

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