Results 21 to 30 of about 48,679 (293)
Marine Drugs, 2020 Four new indolyl diketopiperazines, aspamides A–E (1–4) and two new diketopiperazines, aspamides F–G (5–6), along with 11 known diketopiperazines and intermediates were isolated from the solid culture of Aspergillus versicolor, which is an endophyte with
Yi Ding +5 more
doaj +1 more source
Medical Sciences Forum, 2022 Liver damage is a common issue associated with synthetic cathinones abuse. Indeed, human stem cell-derived hepatocyte-like cells (HLCs) have been used as alternative in vitro models for hepatotoxicity studies, due to their ability to maintain a stable ...
Barbara Silva +6 more
doaj +1 more source
Profiling the Nematicidal Activity of Linear and Cyclic Compounds on the Pinewood Nematode
Chemistry Proceedings, 2021 The pinewood nematode (PWN), Bursaphelenchus xylophilus, has become one of the most damaging pests to forest health in Asia and Europe. In the screening for sustainable biopesticides, research has focused on highly active secondary metabolites.
Jorge M. S. Faria +4 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022 About half of the drugs currently produced are chiral compounds, and about 90 % of these compounds are sold as racemates, consisting of an equimolar mixture of two enantiomers.
Ye. O. Karpun +3 more
doaj +1 more source
MODULATION OF CALCIUM CHANNELS IN ARTERIAL SMOOTH-MUSCLE CELLS BY DIHYDROPYRIDINE ENANTIOMERS [PDF]
, 1993 The actions of the optical enantiomers of BAY K 8644 and Sandoz 202,791 were studied on barium inward currents recorded using the whole-cell configuration of the patch clamp technique from enzymatically isolated smooth muscle cells from the rabbit ear ...
S Hering +7 more
core +1 more source
Frontiers in Marine Science, 2015 Amino acid (AA) compositions were determined for bacteria-sized particles and particulate organic matter (POM) collected in offshore regions of the western North Pacific.
Hiroyuki eTakasu, Toshi eNagata
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Enantiomers of chiral fungicides usually display different toxic effects on nontarget organisms in the surrounding environment, although there are rare reports on the enantioselective toxicity of metconazole (MEZ) to aquatic organisms, such as ...
Ling Li, Peiling Huang, Junjie Li
doaj +1 more source
Characterization of the conglomerate form of acetyl-dl-leucine by thermal analysis and solubility measurements [PDF]
, 2012 Starting from a mixture of enantiomers in solution, crystallization can generate different types of crystals. In order to determine which type of crystal is obtained in the case of acetylleucine, an active pharmaceutical ingredient (API), analytical ...
B. Biscans +9 more
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Pharmacokinetic study of praziquantel enantiomers and its main metabolite R-trans-4-OH-PZQ in plasma, blood and dried blood spots in Opisthorchis viverrini-infected patients [PDF]
, 2016 Praziquantel (PZQ) is the treatment of choice for infections with the liver fluke Opisthorchis viverrini, a major health problem in Southeast Asia. However, pharmacokinetic (PK) studies investigating the disposition of PZQ enantiomers (R- and S-PZQ) and ...
Jennifer Keiser +15 more
core +1 more source
On the Separation of Enantiomers by Drift Tube Ion Mobility Spectrometry
, 2022 Racemic mixtures of twelve common α-amino acids and three chiral drugs were tested for the separation of their enantiomers by drift tube ion mobility spectrometry (IMS)-quadrupole mass spectrometry (QMS) by introducing chiral selectors into the buffer ...
Markus, Doerr +1 more
core +1 more source