Results 41 to 50 of about 55,056 (232)
Molecules, 2020 The chiral separation of etoxazole enantiomers on Lux Cellulose-1, Lux Cellulose-3, Chiralpak IC, and Chiralpak AD chiral columns was carefully investigated by normal-phase high performance liquid chromatography and reverse-phase high performance liquid ...
Ping Zhang +7 more
doaj +1 more source
Two Pairs of 7,7′-Cyclolignan Enantiomers with Anti-Inflammatory Activities from Perilla frutescens
Molecules, 2022 Perilla frutescens (L.) Britt. (Labiatae), a medicinal plant, has been widely used for the therapy of multiple diseases since about 1800 years ago. It has been demonstrated that the extracts of P.
Jing Zuo +6 more
doaj +1 more source
“Smelltronics”—From Gas to Smell Sensing
Advanced Materials, EarlyView.The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono +7 more
wiley +1 more source
Counterion Dynamics in Chiral Supramolecular Polymerization
Angewandte Chemie, EarlyView.A single counterion acts as a dynamic structural element directing pathway‐dependent supramolecular polymerization. Subtle counterion repositioning governs molecular packing, aggregate morphology, supramolecular chirality, and asymmetry amplification. ABSTRACT Counterions have been studied in a broad range of chemical and biological systems, and their ...
Camila Montañez‐Moyano +3 more
wiley +2 more sources
, 2021 International audienceOnly in exceptional cases, a pair of enantiomers do form a series of mixed crystals. The most well-known of the exceptions is the system laevorotatory carvoxime+dextrorotatory carvoxime; its properties are discussed in some detail ...
I. B. Rietveld +3 more
core +2 more sources
Tropical Medicine and Infectious Disease, 2022 Malaria is one of the deadliest tropical diseases, especially causing havoc in children under the age of five in Africa. Although the disease is treatable, the rapid development of drug resistant parasites against frontline drugs requires the search for ...
Che Julius Ngwa +11 more
doaj +1 more source
Engineering Metal‐Pocket Cooperativity in Single‐Atom COF Nanozymes for Selective Cascade Catalysis
Advanced Materials, EarlyView.A multilevel programming strategy is developed to engineer single‐atom COF nanozymes with tunable metal centers and chiral pockets inspired by heme–pocket cooperativity. This approach enables controlled metal–pocket interplay for asymmetric cascade catalysis, delivering high activity, selectivity, and recyclability in an asymmetric oxidation–aldol ...
Ziping Li +7 more
wiley +1 more source
Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates
Angewandte Chemie, EarlyView.An alkyne‐tagged ethanolamine analog (AlkEA) enables bioorthogonal, metabolic labeling of endogenous phosphatidylethanolamine (PE) and its protein modifications. AlkEA is incorporated into PE via the Kennedy pathway, allowing CuAAC‐based visualization of PE and affinity capture of PE‐conjugated LC3, ubiquitin, and GPI‐anchored proteins.
Yuan‐Ting Cho +5 more
wiley +2 more sources
Advanced Optical Materials, EarlyView.This work presents an electrically controllable approach to spin–valley polarization in monolayer WS2 by integrating it with a dual‐mode liquid crystal laser. Applying an external field triggers phase transitions that switch the laser emission between helicity‐defined band‐edge lasing and unpolarized random lasing.
Yu‐Chuan Tsao +3 more
wiley +1 more source
Angewandte Chemie, EarlyView.Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey +13 more
wiley +2 more sources