Results 51 to 60 of about 48,679 (293)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

The Phenomenon of Self-Induced Diastereomeric Anisochrony and Its Implications in NMR Spectroscopy

Molecules, 2023
Nuclear magnetic resonance (NMR) spectroscopy is an analytical technique largely applied in the analysis of discrimination processes involving enantiomeric substrates and chiral agents, which can interact with the analyte either via covalent bonding or ...
Federica Aiello, Gloria Uccello Barretta, Federica Balzano, Fabio Spiaggia   +3 more
doaj   +1 more source

enantiomer [PDF]

, 2014
Citation: 'enantiomer' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.E02069 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Ketamine: A tale of two enantiomers [PDF]

Journal of Psychopharmacology, 2020
The discovery of the rapid antidepressant effects of the dissociative anaesthetic ketamine, an uncompetitive N-Methyl-D-Aspartate receptor antagonist, is arguably the most important breakthrough in depression research in the last 50 years. Ketamine remains an off-label treatment for treatment-resistant depression with factors that limit widespread use ...
Luke A Jelen, Allan H Young, James M Stone   +2 more
openaire   +3 more sources

Chirality and Organization of Adsorbates Modify Surface Phonon Dynamics

Advanced Functional Materials, EarlyView.
Chirality and molecular organization are shown to influence surface phonon dynamics in gold films. Time‐resolved Joule heating measurements reveal that ordered homochiral monolayers increase the Debye temperature and disordered layers reduce it, while ordered racemic controls have no effect.
Meital Ozeri, Eugenia Pyurbeeva, Shira Yochelis, Jonas Fransson, Ronnie Kosloff, Oded Millo, Yossi Paltiel   +6 more
wiley   +1 more source

Chiral Metasurfaces: A Review of the Fundamentals and Research Advances

Applied Sciences, 2023
Chirality, the absence of mirror symmetry, is predominant in nature. The chiral nature of the electromagnetic field behaves differently with chiral matter for left circularly polarized and right circularly polarized light. The chiroptical behavior in the
Semere Araya Asefa, Sangmin Shim, Myeongsu Seong, Dasol Lee   +3 more
doaj   +1 more source

Application of Ibuprofen Sodium Dihydrate for Thermochemical Energy Storage

Advanced Functional Materials, EarlyView.
Ibuprofen sodium dihydrate is introduced as a durable organic salt hydrate for low‐temperature thermochemical energy storage, operating within 60°C–110°C with high energy density. At the material level, it delivers ∼99.9% cycling efficiency over 150 cycles without deliquescence, enabled by a dual energy‐storage mechanism coupling dehydration and phase ...
Kavin Chakravarthy Thangaraj, Hannah F. Chang, Shannon J. Lee, Mark E. Bowden, J. David Bazak, Vaithiyalingam Shutthanandan, Venkateshkumar Prabhakaran, Xiao Zhang, David M. Reed, Ajay S. Karakoti, Vijayakumar Murugesan   +10 more
wiley   +1 more source

Resolutions of racemates by crystallization : additives and attrition [PDF]

, 2009
Although biological processes in simple bacteria or rather complex animals such as humans exclusively form left or right-handed molecules, in a normal chemical reaction, carried out in a laboratory, equal amounts of left and right-handed molecules ...
Leeman, Michel Sebastiaan,, Leeman, Michel Sebastiaan   +1 more
core  

Azaporphyrinoid‐Based Photo‐ and Electroactive Architectures for Advanced Functional Materials

Advanced Materials, EarlyView.
A long‐standing collaboration between the Torres and Guldi groups has yielded diverse azaporphyrinoid‐based donor‐acceptor nanohybrids with promising applications in solar energy conversion. This conspectus highlights key molecular platforms and structure‐function relationships that govern light and charge management, supporting the rational design of ...
Jorge Labella, Kobra Azizi, Dirk M. Guldi, Tomás Torres   +3 more
wiley   +1 more source

Chiral Microneedle Arrays With Terahertz Chiroptical Activity With Chiral‐Plasmon‐Chiral‐Phonon Resonance

Advanced Materials, EarlyView.
ABSTRACT Microneedle arrays (MNAs) is a rapidly emerging technology with broad biomedical applications in drug delivery and biosensing. With sub‐millimeter dimensions and periodicity, MNAs possess geometries nearly ideal for biomedical devices operating within the terahertz (THz) spectral window.
Sang Hyun Lee, Hong Ju Jung, John Kim, Bum Chul Park, Caio V. C. R. da Silva, André F. de Moura, Nicholas A. Kotov   +6 more
wiley   +1 more source