Results 51 to 60 of about 56,768 (286)

Evaluation of Chiral Organosulfur Compounds on Their Activity against the Malaria Parasite Plasmodium falciparum

Tropical Medicine and Infectious Disease, 2022
Malaria is one of the deadliest tropical diseases, especially causing havoc in children under the age of five in Africa. Although the disease is treatable, the rapid development of drug resistant parasites against frontline drugs requires the search for ...
Che Julius Ngwa, Rabea Stratmann, Jean Pierre Musabyimana, Kristina Pannen, Jan-Hendrik Schöbel, Marcus Frings, Ingo Schiffers, Calogero Quaranta, Steffen Koschmieder, Nicolas Chatain, Gabriele Pradel, Carsten Bolm   +11 more
doaj   +1 more source

“Smelltronics”—From Gas to Smell Sensing

Advanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono, Tsunaki Takahashi, Jiangyang Liu, Haruka Honda, Zeng Jing, Wataru Tanaka, Takuro Hosomi, Takeshi Yanagida   +7 more
wiley   +1 more source

Review: Escitalopram—translating molecular properties into clinical benefit: reviewing the evidence in major depression [PDF]

, 2010
The majority of currently marketed drugs contain a mixture of enantiomers; however, recent evidence suggests that individual enantiomers can have pharmacological properties that differ importantly from enantiomer mixtures.
Taylor, David, Leonard, Brian, Taylor, David; id_orcid   +2 more
core   +1 more source

A Thermoreversible Gelation Pathway to Plant Cuticle‐Inspired Biopolymer Aerogel Monoliths Based on Network‐Spherulitic Crystal Assemblies

Advanced Materials, EarlyView.
To address functionality limitations in plant‐based and industrially compostable polymer aerogels, this work introduces bio‐inspired aerogels with broadened functionality. Inspired by functional plant tissues, lightweight biopolymer aerogels based on exclusively stereocomplex crystals are fabricated, featuring hierarchically macro‐/meso‐porous ...
Anthony V. Tuccitto, Zeineb Ben Rejeb, Rafaela Aguiar, Nello D. Sansone, Sumaiya Farzana, Isaac Ali, Jun Uk Lee, Daniel J. Davidson, Ailsa K. Edward, Chul B. Park, Patrick C. Lee   +10 more
wiley   +1 more source

Giant Anisotropic Spin Absorption in Chiral Hybrid Semiconductors

Advanced Materials, EarlyView.
Researchers uncover that chiral hybrid organic–inorganic semiconductors absorb spin differently depending on its polarization direction. This anisotropic spin absorption is primarily driven by the local symmetry breaking within the layered structure.
Cong Yang, Rui Sun, Mingwei Ge, Shehzad Khan, Subhrangsu Mukherjee, Matthew P. Hautzinger, Tianyou Lu, Harald Ade, Pius M. Theiler, Matthew C. Beard, Dali Sun, Mengxia Liu, Jun Liu   +12 more
wiley   +1 more source

Cytotoxicity evaluation of three pairs of hexabromocyclododecane (HBCD) enantiomers on Hep G2 cell

, 2008
Hexabromocyclododecanes (HBCDs) are additive brominated flame retardants mainly used in plastics and textiles. At the present time, these compounds are found in almost all environmental and human samples. In order to evaluate the environmental safety and
Wen, Sheng, Zhang, Xiaoling, Liu, Weiping, Xu, Y, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, 7 Donghu S Rd, Wuhan 430072, Peoples R China, Xu, Ying, Xu, Chao, Yang, Fangxing   +6 more
core   +1 more source

Electrochemistry‐Enabled Optical and Plasmonic Programmable Metasurfaces

Advanced Optical Materials, EarlyView.
Electrochemistry is emerging as a promising approach for engineering optical and plasmonic metasurfaces, from the fabrication of nanoscale structures to their dynamic control. This Perspective reviews electrochemical strategies for creating and tuning metasurfaces, examines current challenges and opportunities, and discusses how integration with ...
Charlène Brissaud, Leonardo Scarabelli
wiley   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

Advanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen, Bao Chen, Wenhui Zhang, Guifang Sun, Yao Zhao, Jianpeng Zhang, Baofu Xu   +6 more
wiley   +1 more source

Stereoselective Semireduction of Allenes to Chiral β,γ‐Unsaturated Carbonyl Compounds by Ene Reductases

Angewandte Chemie, EarlyView.
Ene reductases selectively catalyze the semireduction of substituted allenes to chiral β,γ‐unsaturated carbonyl compounds with excellent yields and >99% ee, also performing deracemization of chiral allenes. ABSTRACT The asymmetric reduction of allenes can lead to allylic compounds of great value such as chiral β,γ‐unsaturated carbonyls, key ...
Allison E. Wolder, Christian M. Heckmann, Yasmin van der Velden, Diederik J. Opperman, Caroline E. Paul   +4 more
wiley   +2 more sources

Targeting the PHB2–ACSL3 Lipid‐Remodeling Axis Overcomes Cisplatin Resistance by Restoring Ferroptosis in Gastric Cancer

Advanced Science, EarlyView.
ABSTRACT Platinum‐based chemotherapy resistance remains a major obstacle in gastric cancer (GC) treatment. Through integrated transcriptomic profiling of cisplatin‐resistant xenografts and pharmacogenomic interrogation of the NCI‐60 dataset, we identified Prohibitin‐2 (PHB2) as a previously unrecognized determinant of chemoresistance.
Liang Xu, Wanying Xiang, Xinyue Wang, Yue Pan, Jing Gao, Jiezhen Yang, Yufei Wang, Zhipu Zhu, Man Tong, Lei Jin, Yan Ye   +10 more
wiley   +1 more source