Results 41 to 50 of about 86,276 (266)

Processes To Separate Enantiomers [PDF]

open access: yesAngewandte Chemie International Edition, 2014
AbstractThe provision of pure enantiomers is of increasing importance not only for the pharmaceutical industry but also for agrochemistry and biotechnology. In general, there are two rival approaches to provide pure enantiomers. The “chiral” approach is based on developing an asymmetric synthesis of just one of the enantiomers, while the “racemic ...
Lorenz, H., Seidel-Morgenstern, A.
openaire   +3 more sources

Diastereoisomer-Specific Biotransformation of Hexabromocyclododecanes by a Mixed Culture Containing Dehalococcoides mccartyi Strain 195

open access: yesFrontiers in Microbiology, 2018
Hexabromocyclododecane (HBCD) stereoisomers may exhibit substantial differences in physicochemical, biological, and toxicological properties. However, there remains a lack of knowledge about stereoisomer-specific toxicity, metabolism, and environmental ...
Yin Zhong   +15 more
doaj   +1 more source

A Stern-Gerlach separator of chiral enantiomers based on the Casimir-Polder potential

open access: yes, 2018
We propose a method to separate enantiomers using parity violation in the Casimir-Polder potential between chiral mirrors and chiral molecules. The proposed setup involves a molecular beam composed of chiral molecules passing through a planar cavity ...
Fumika Suzuki   +10 more
core   +1 more source

Pharmacokinetic study of praziquantel enantiomers and its main metabolite R-trans-4-OH-PZQ in plasma, blood and dried blood spots in Opisthorchis viverrini-infected patients [PDF]

open access: yes, 2016
Praziquantel (PZQ) is the treatment of choice for infections with the liver fluke Opisthorchis viverrini, a major health problem in Southeast Asia. However, pharmacokinetic (PK) studies investigating the disposition of PZQ enantiomers (R- and S-PZQ) and ...
Duthaler, Urs   +7 more
core   +2 more sources

MODULATION OF CALCIUM CHANNELS IN ARTERIAL SMOOTH-MUSCLE CELLS BY DIHYDROPYRIDINE ENANTIOMERS [PDF]

open access: yes, 1993
The actions of the optical enantiomers of BAY K 8644 and Sandoz 202,791 were studied on barium inward currents recorded using the whole-cell configuration of the patch clamp technique from enzymatically isolated smooth muscle cells from the rabbit ear ...
Bolton, TB   +3 more
core   +1 more source

Complete homochirality induced by the nonlinear autocatalysis and recycling

open access: yes, 2003
A nonlinear autocatalysis of a chiral substance is shown to achieve homochirality in a closed system, if the back-reaction is included. Asymmetry in the concentration of two enantiomers or the enantiometric excess increases due to the nonlinear ...
Bada J. L.   +12 more
core   +1 more source

Chiral Separation and Determination of Etoxazole Enantiomers in Vegetables by Normal-Phase and Reverse-Phase High Performance Liquid Chromatography

open access: yesMolecules, 2020
The chiral separation of etoxazole enantiomers on Lux Cellulose-1, Lux Cellulose-3, Chiralpak IC, and Chiralpak AD chiral columns was carefully investigated by normal-phase high performance liquid chromatography and reverse-phase high performance liquid ...
Ping Zhang   +7 more
doaj   +1 more source

Two Pairs of 7,7′-Cyclolignan Enantiomers with Anti-Inflammatory Activities from Perilla frutescens

open access: yesMolecules, 2022
Perilla frutescens (L.) Britt. (Labiatae), a medicinal plant, has been widely used for the therapy of multiple diseases since about 1800 years ago. It has been demonstrated that the extracts of P.
Jing Zuo   +6 more
doaj   +1 more source

Enantiomeric separation of four pairs of alkaloids by using a C18 column tandem polysaccharide-based chiral column

open access: yesReviews in Analytical Chemistry
Alkaloid enantiomers have different physiological and pharmacological effects, and different chiral compositions have a large impact on cigarette sensory and use safety.
Si Xiaoxi   +10 more
doaj   +1 more source

Evaluation of Chiral Organosulfur Compounds on Their Activity against the Malaria Parasite Plasmodium falciparum

open access: yesTropical Medicine and Infectious Disease, 2022
Malaria is one of the deadliest tropical diseases, especially causing havoc in children under the age of five in Africa. Although the disease is treatable, the rapid development of drug resistant parasites against frontline drugs requires the search for ...
Che Julius Ngwa   +11 more
doaj   +1 more source

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