Results 131 to 140 of about 119,652 (298)

Hofmann Degradation of Asparagine and Glutamine as an Efficient Approach for the Synthesis of Derivatized Lysine Homologs

European Journal of Organic Chemistry, EarlyView.
A practical and scalable route to C1 and C2 lysine homologs has been developed using Hofmann degradation of N‐protected L‐asparagine and L‐glutamine as the key step. These short‐tether scaffolds enable efficient synthesis of diverse Fmoc‐protected noncanonical amino acids (ncAAs) bearing donor, acceptor, redox‐active, and fluorescent residues.
Adelaide R. Mashweu, François J. De Beer, Jolien Bertouille, Steven Ballet, Charlotte Martin, Ulrich Hennecke, Charlene Marais, Vladimir A. Azov   +7 more
wiley   +1 more source

Beyond L-Proline: Investigation into the Catalytic Properties of Other Natural Amino Acids in an Organocatalytic Warfarin Synthesis

Chemistry
Proline is considered the model organocatalytic amino acid. However, other naturally occurring amino acids remain a potent and perhaps overlooked source of organocatalytic potential.
Anna I. Wurz, Arhemy Franco-Gonzalez, Naomi R. Benson, Hope L. Jankowski, Sierra N. Carr, Ketan Chamakura, Lizbeth Chirinos, Sydney P. Coll, Kayla F. Ivory, Trinity J. Lamb, Shaya LeBauer, Grace L. McPherson, Thanh Nguyen, Jeimy Nolasco Guevara, Lily N. Parsad, Phuong Pham, Emma G. Piner, Kaci Richardson, Abdelhadi Bendjellal, Chelsea McRae, Robert M. Hughes   +20 more
doaj   +1 more source

The effect of alcohol on the performance of lipase-immobilized enzymatic membrane reactor for esterification of (R,S)-ketoprofen [PDF]

, 2006
The effect of alcohols on the performance of lipase-immobilized enzymatic membrane reactor (EMR) for enantioselective esterification of (R,S)-ketoprofen has been studied. In this work, mixed solvent medium was used and the (R)-ketoprofen was reacted with
Bhatia, Subhash, Chuan Fu, Kian, Harun @ Kamaruddin, Azlina, Ong, Ai Lien   +3 more
core  

Photochemical Decatungstate‐Catalyzed Hydroacylation of Maleimides

European Journal of Organic Chemistry, EarlyView.
A photocatalytic protocol to access substituted succinimides via tetra‐n‐butylammonium decatungstate photocatalysis is reported. This direct radical‐driven hydroacylation of a variety of N‐substituted maleimides shows tolerance to various aldehydes (or alkanes), affording differentially substituted succinimides in high yields. Succinimides constitute a
Manos V. G. Lantzanakis, Naya A. Stini, Christoforos G. Kokotos   +2 more
wiley   +1 more source

1,2‐Diazetidines − Structure, Synthesis, and Functionalization

European Journal of Organic Chemistry, EarlyView.
1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
wiley   +1 more source

Enantioselective cycloaddition reactions

ChemInform, 1991
Publisher Summary This chapter reviews the cycloadditions reactions because they are popular, widely used, and also constitutes enormous body of chemistry. The chapter focuses on the landmark achievements as well as state-of-the-art examples of relevant chemistry.
openaire   +2 more sources

Porcine Liver Esterase‐Catalyzed Dynamic Kinetic Resolution of a Lactone‐Bridged Biaryl: Impact of Organic Cosolvents on Enantioselectivity

European Journal of Organic Chemistry, EarlyView.
A stereolabile lactone‐bridged biaryl enables dynamic kinetic resolution to provide a conformationally stable ring‐opened biaryl. A significant positive effect of water‐immiscible organic cosolvents on the enantioselectivity in a reaction catalyzed by porcine liver esterase has been discovered for the first time.
Neha Dhiman, Anke Hummel, Kyohei Kanomata, Yoshinari Sawama, Tohru Taniguchi, Harald Gröger, Shuji Akai   +6 more
wiley   +1 more source

Unlocking the Functionalization and Reactivity of Ethylene Bridges in [2.2]Paracyclophanes: Strategies and Challenges

European Journal of Organic Chemistry, EarlyView.
Bridging the gap. Beyond deck functionalization, the ethylene bridges of [2.2]paracyclophanes offer a largely unexploited reactivity landscape. This review showcases strategies to functionalize these bridges and leverage them to build novel cyclophane architectures.
Rongyu Sun, Tamara Ye, Laurent Micouin, Erica Benedetti   +3 more
wiley   +1 more source

Isotellurourea‐Catalyzed Enantioselective (4+2)‐Heterocycloadditions of But‐2‐ynoates and Michael Acceptors

European Journal of Organic Chemistry, EarlyView.
Isotelluroureas allow for the use of alkynoates for asymmetric (4+2)‐heterocycloadditions with different Michael acceptors. Alk‐2‐ynoates are readily available starting materials which, in principle, can be utilized for cycloadditions in analogy to structurally similar allenoates.
Anna Scheucher, Mario Waser
wiley   +1 more source

Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications

Food Bioengineering, EarlyView.
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang, Ruoke Li, Yixuan Xie, Hanya Zhang, Xiaoyu Huang, Siwei Chen, Weixin Xu, Yueling Liu   +7 more
wiley   +1 more source