Results 121 to 130 of about 14,649 (249)

Diphenyl Disulfide‐Promoted Racemization of 1‐Arylethanols for Photobiocatalytic Dynamic Kinetic Resolution

European Journal of Organic Chemistry, EarlyView.
Purple‐light activation of aggregated diphenyl disulfide unlocks the photocatalyst‐free racemization of 1‐arylethanols. The resulting sulfur radical process operates under mild conditions and couples with the enzymatic acylation by Candida antarctica lipase B in a photobiocatalytic dynamic kinetic resolution, revealing new opportunities for sulfur ...
Cristina Guolo, Stefano Parisotto, Cristina Prandi   +2 more
wiley   +1 more source

Copper-Catalyzed Enantioselective Synthesis of Chiral Selenium-Based Versatile Synthons. [PDF]

ACS Cent Sci
Huang Q, Chen JX, Tang YP, Shui TH, Yi JX, Zhang CG, Dai L.   +6 more
europepmc   +1 more source

Copper‐Catalyzed α‐Carbamoylation of Cyclic β‐Ketoesters

European Journal of Organic Chemistry, EarlyView.
Cu(II) salt‐catalyzed reaction of cyclic β‐ketoesters with isocyanates afforded hitherto inaccessible α‐substituted β,β’‐dicarbonyl amides possessing an all‐carbon quaternary center. A copper‐catalyzed, base‐free α‐carbamoylation of cyclic β‐ketoesters with isocyanates has been developed.
Yihao Shi, Akihiro Sakama, Kazuaki Kudo
wiley   +1 more source

Diarylethene‐Containing Photoswitchable Analogues of Tubulysins—Design, Synthesis, Biological, and Structural Evaluation

European Journal of Organic Chemistry, EarlyView.
Diarylethene‐containing cyclic tubulysin analogues were designed, synthesized, and evaluated as light‐responsive cytotoxic agents. One analogue showed reversible photoswitching, photoregulated tubulin polymerization inhibition, and photoform‐dependent cytotoxicity.
Anna Iampolska, Sergii Afonin, Oleg Babii, Mahri Park, Juan Estévez‐Gallego, Michel O. Steinmetz, Andrea E. Prota, Anne S. Ulrich, David R. Spring, Igor V. Komarov   +9 more
wiley   +1 more source

Catalytic Enantioselective Synthesis of 1,1-Disubstituted Isochromans. [PDF]

J Am Chem Soc
Li Z, Banerjee S, Zhu Z, Smajlagic I, Galante M, Dobrzycki Ł, Vetticatt MJ, Seidel D.   +7 more
europepmc   +1 more source

Cyclodextrins as Chiral Selectors in Capillary Electrophoresis—Recent Developments in Understanding Analyte Complexation and Applications in Pharmaceutical Analysis

ELECTROPHORESIS, EarlyView.
Cyclodextrins are the most often applied chiral selectors in CE enantioseparations. In combination with NMR spectroscopy and molecular modeling, studies for an understanding of chiral recognition underlying enantioseparations have been performed.
Gerhard K. E. Scriba
wiley   +1 more source

Enantioselective Synthesis of Spirolactones and Spirolactams Under Low Catalyst Loadings. [PDF]

J Am Chem Soc
Saito T, Navarro A, Davies HML.
europepmc   +1 more source

Chiral HPLC Separation of Phosphonothrixin and Phosphonate Derivatives and Electronic Circular Dichroism Characterization of the Isolated Enantiomers

ELECTROPHORESIS, EarlyView.
Natural compound phosphonothrixin's herbicidal activity resides exclusively in its (S)‐enantiomer, yet existing enantioselective syntheses are cumbersome, and direct chiral LC separation is hampered by the compound's high polarity, lack of aromatic groups, and metal chelation–induced peak tailing.
Mirna Maalouf, Maximilian Knab, Leon Gessner, Marc Engelhardt, Stella Friedrich, Harald Gross, Frank Boeckler, Chambers C. Hughes, Michael Lämmerhofer   +8 more
wiley   +1 more source

Enantioselective synthesis of configurationally stable [5]helicenes containing 1,2-azaborine units. [PDF]

Chem Sci
Olguin C, Tabacaru C, Besse L, Simon M, Golz C, Humanes M, Fernández-Rodríguez MA, García-García P, Mücke M, Mata RA, Alcarazo M.   +10 more
europepmc   +1 more source

Novel tetronamides derived from mucobromic acid: synthesis, structural elucidation, DFT calculations and phytotoxic activity

Pest Management Science, EarlyView.
The acyclic mucobromic acid, activated by (1S)‐(+)‐10‐camphorsulfonic acid, afforded the chiral compound 1b, precursor for aza‐Michael addition/elimination on the butenolide yielding tetronamides 2b‐7b. Their relative SRSR configuration was confirmed by the spectrometric methods, DFT calculation and statistical methods.
Kamylla CF Faria, Vitor C Baia, Elson S Alvarenga   +2 more
wiley   +1 more source