Results 141 to 150 of about 2,677,083 (277)

Enantioselective Synthesis of Fluorinated Indolizidinone Derivatives

Enantioselective Synthesis of Fluorinated Indolizidinone ...
Gaviña Rueda, Daniel, Sánchez Roselló, María, Díaz-Oltra, Santiago, Escolano Pérez, Marcos, del Pozo Losada, Carlos   +4 more
core   +1 more source

Stereochemical Control in the Matteson Reaction

Chemistry – A European Journal, EarlyView.
The Matteson homologation is a highly versatile method for the stereoselective insertion of carbenoids into boronic esters. Through iterative application of the process, complex chiral molecules can be synthesized. The stereoselectivity of the reaction is determined by a chiral diol incorporated in the boronic ester.
Hae Mo Lee, Christoph Hirschhäuser
wiley   +1 more source

Cyclopropylamine‐Derived Distonic Iminium Radicals: Photoinduced Strategies in Chemo‐ and Stereo‐Selective Synthesis

Chemistry – A European Journal, EarlyView.
Cyclopropylamines have emerged as powerful photocatalytic building blocks. Upon light‐induced single‐electron oxidation, they undergo strain‐release ring opening to generate distonic iminium radicals that enable diverse transformations, including ring‐opening functionalization, formal [3 + 2] cycloadditions, radical cascades, and asymmetric bond ...
Maria Chiara Cabua, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +3 more
wiley   +1 more source

Chiral Pyrazolinylidene Complexes for Asymmetric Catalysis

Chemistry – A European Journal, EarlyView.
The synthesis and application of pyrazolin‐5‐ylidene NHC chiral‐at‐ruthenium catalysts is reported. The strong donating pyrazolin‐5‐ylidene ligands led to highly electron rich ruthenium complexes, which showed excellent catalytic activity and enantioselectivity in the intramolecular aziridination of an alkene.
Felix Möller, Nemrud Demirel, Thomas Krüger, Linus Plohnke, Jennifer Schröder, Sergei I. Ivlev, Eric Meggers   +6 more
wiley   +1 more source

The Mechanism of Visible‐Light Photochemical Rearrangements of Conjugated Amide Enolates

Chemistry – A European Journal, EarlyView.
Visible light irradiation of extended enolates of N‐benzylamides leads to homolytic C─N Bond cleavage, generating a biradical. Computational and mechanistic studies suggest rapid radical recombination within a solvent cage to give either ring‐expanded or rearranged products. ABSTRACT Deprotonation of conjugated amides forms colored solutions of lithium
James Mortimer, William Terry‐Wright, Basile F. E. Curchod, Jonathan Clayden   +3 more
wiley   +1 more source

Synthesis and Structures of Novel Chiral Cyclic Hypervalent Iodine(III) Reagents for Metal‐Free Ligand‐Transfer Reactions

Chemistry – A European Journal, EarlyView.
Several new chiral cyclic hypervalent iodine(III) reagents have been synthesized and characterized. Carbon‐based ligands were successfully installed onto the hypervalent iodine centers, giving thus access to novel chiral cyano‐, trifluoromethyl‐ or alkynyl‐bearing λ3‐iodanes.
Emmanuel Valzer, Jean‐Marc Sotiropoulos, Karinne Miqueu, Laurent Pouységu, Stéphane Quideau   +4 more
wiley   +1 more source

Rhodium‐Catalyzed Synthesis of Enantioenriched α‐Substituted Primary Amines Through Asymmetric Transfer Hydrogenation

Chemistry – A European Journal, EarlyView.
Enantioenriched α‐substituted primary amines are efficiently prepared by rhodium‐catalyzed asymmetric transfer hydrogenation of ortho‐hydroxyaryl N─H imines under mild conditions using a low catalyst loading and ammonium formate as the hydrogen source in high yields (up to 99%) and enantioselectivities (up to 99% ee).
Chonghuo Liu, Guillaume Lefèvre, Qin Yin, Phannarath Phansavath, Virginie Ratovelomanana‐Vidal   +4 more
wiley   +1 more source

Synthesis of Chiral‐at‐Sulfur(VI) Sulfonimidamide Brønsted Acids

Chemistry – A European Journal, EarlyView.
A simple, modular route to chiral‐at‐sulfur(VI) Brønsted acids is described, delivering S‐chiral sulfonimidamides, C2‐symmetric acids, and BINOL‐based hybrid systems through stereospecific reactions of sulfonimidoyl fluorides and chlorides. ABSTRACT Herein, we report an efficient and simple strategy to access diverse chiral‐at‐sulfur(VI) Brønsted acids.
Yu Han, Natassa Lional, Dieuwertje E. Streefkerk, Jesse M. S. Goed, Bo Chen, Han Zuilhof, Fedor M. Miloserdov   +6 more
wiley   +1 more source

Carboxylate–Probase Catalyzed Favorskii Reaction

Chemistry – A European Journal, EarlyView.
Stronger together: A combination of a carboxylate catalyst and a silylating agent generates a stronger base catalyst for a metal‐free catalytic addition of alkynes to aldehydes and ketones under chemoselective, O‐silylative conditions. The reaction is proposed to proceed via quaternary ammonium (Q+) cation – acetylide anion ion pairs, with chiral ...
Anton Bannykh, Sanna M. Stenfors, Anton Nechaev, John M. Fiskari, Petri M. Pihko   +4 more
wiley   +1 more source

Thiamine Diphosphate‐Dependent Biocatalysis in the 21st Century

Chemistry – A European Journal, EarlyView.
This account summarizes the major discoveries and recent advances, highlighting the biocatalytic abilities, mechanistic studies, and feature‐based classification that are shaping emerging perspectives on thiamine diphosphate (ThDP)‐dependent catalysis.
Lucrezia Lanza, Daniela Bjarnesen, Michael Müller   +2 more
wiley   +1 more source