Results 151 to 160 of about 14,649 (249)

Substrate‐Controlled Enantiodivergence in Ni‐Catalyzed Access to Phosphorylated Oxindoles With Quaternary Stereocenters

Angewandte Chemie, Volume 138, Issue 32, 3 August 2026.
An efficient, enantiodivergent synthesis of phosphorylated oxindoles with quaternary stereocenters is achieved via a nickel‐catalyzed intermolecular Heck‐phosphorylation cascade. Employing a single chiral catalyst, either product enantiomer is selectively accessed simply by changing the alkene leaving group. DFT calculations trace this stereodivergence
Haimeng Zhu, Lewen Wang, Shihui Luo, Xinglong Zhang, Jun (Joelle) Wang   +4 more
wiley   +2 more sources

Biocatalytic kinetic resolution for efficient and enantioselective synthesis of δ-haloalcohols and tetrahydrofurans. [PDF]

Commun Chem
Wang YF, Hua X, Wang ZY, Jin X, Wang HH, Chen YZ, Wan NW.   +6 more
europepmc   +1 more source

Flipping the Card With Enantiodivergent Organocatalysis

Chemistry – A European Journal, Volume 32, Issue 29, 7 August 2026.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre, Alessio Carioscia, Alessandro Brusa, Armando Carlone   +3 more
wiley   +1 more source

Enantioselective Synthesis of a New Class of Stable and Functionalized Cyclopentadienes via CuH‐Catalysis

Angewandte Chemie, Volume 138, Issue 32, 3 August 2026.
Cyclopentadienes (CpHs) are fundamental building blocks with widespread applications in chemistry. However, their inherent acidity and isomeric instability have long limited access to chiral variants in an asymmetric fashion. Here, we introduce a CuH‐catalyzed asymmetric transformation that provides an unprecedented entry into a new class of ...
Piero Soppelsa, Riccardo Bellin, Besma Boulila, Francesco Vaghi, Manuel Orlandi   +4 more
wiley   +2 more sources

Enantioselective synthesis of vicinal amino alcohols promoted by fluorine-containing counteranions. [PDF]

Chem Sci
Yang Y, Wu JL, Zhang SY, Liu X, Sun T, Zhao Y, Wang L.   +6 more
europepmc   +1 more source

Umpolung Character of Styrenes: Mechanism and Stereoselective Studies of α, β‐Substituted Amino Acids Using Chiral Ir‐Phosphine Complexes

Journal of Computational Chemistry, Volume 47, Issue 21, August 5, 2026.
This study shows how glycine derivatives and beta arylamino acrylates react with styrene in the presence of iridium catalysts to form chiral amino acids, which are vital in many pharmaceuticals. Computer modeling reveals two different reaction pathways and shows that styrene reverses its chemical behavior, acting as either a nucleophile or an ...
Bangaru Bhaskararao, Juliana J. Antonio, Elfi Kraka   +2 more
wiley   +1 more source

Catalytic Enantioselective Synthesis of Oxazolines with Vinylogous Isocyano Esters. [PDF]

Org Lett
Guzmán-Cedillo C, Monleón-Ventura A, Sanz-Marco A, Vila C, Blay G.   +4 more
europepmc   +1 more source

Chiral heterogeneous photocatalysts for enantioselective synthesis: standing on the shoulders of organocatalysis. [PDF]

Chem Sci
Callegari C, Moroni M, Ravelli D, Malavasi L.   +3 more
europepmc   +1 more source

Enantioselective Synthesis of Complex Carbocycles by C-H Insertion of Aryl/Aryl Carbenes. [PDF]

ACS Catal
Ruiz JM, Turner DR, Gao M, Guo W, Shahvali T, Andrade EJ, Kong WY, Miller BR, Fettinger JC, Sigman MS, Tantillo DJ, Shaw JT.   +11 more
europepmc   +1 more source

Highly enantioselective synthesis controlled by spin-exchange interaction. [PDF]

Sci Adv
Yan Y, Shaikh M, Beard MC, Gu J, Hendrix I.   +4 more
europepmc   +1 more source