Results 151 to 160 of about 2,677,083 (277)

Trends and Future Directions in Organic Chemistry for Drug Discovery

Chemistry – A European Journal, EarlyView.
Organic synthesis is being reshaped by the convergence of catalytic innovation, automation, artificial intelligence, and emerging therapeutic modalities. Late‐stage functionalization, photoredox and electrochemical methods, biocatalysis, flow chemistry, DELs, and proximity‐based drugs are examined as components of closed‐loop discovery.
Paweł Kozyra, Maciej Masłyk
wiley   +1 more source

Synthesis and Characterization of Hemiindigo‐Based Glycoside and Glycomacrocycle

Chemistry – A European Journal, EarlyView.
Glycosyl hemiindigos: we have synthesized hemiindigo‐functionalized glycoside and glycomacrocycle which are photoswitchable under visible light irradiation with high photoconversion yield and fluorescence emission property in acetonitrile. The conformational constrained glycomacrocycle displayed more efficient photoisomerization.
Guilhem Fontaine, Rémi Métivier, Guillaume Laurent, Régis Guillot, Juan Xie   +4 more
wiley   +1 more source

Modular Assembly of a Biocatalytic Material for Stereoselective C─Si Bond Formation

Chemistry – A European Journal, EarlyView.
A modular, carrier‐free enzyme foam derived from Rhodothermus marinus cytochrome c combines structural stability with catalytic efficiency for stereoselective C─Si bond formation. Streptavidin (STV)‐mediated protein crosslinking creates a robust, self‐supporting materials platform for next‐generation biocatalysis.
Marc F. Münker, Annika J. Weber, Madleen Richter, Jennifer Kühne, Carmen M. Dominguez, Christof M. Niemeyer, Kersten S. Rabe   +6 more
wiley   +1 more source

Structure‐Polarization‐Function Relationship in Oxide Perovskite for Solar‐To‐Fuel Conversion Challenge

EcoEnergy, EarlyView.
Oxide perovskites (ABO3) have emerged as paradigm‐shifting materials for solar energy conversion, uniquely combining ferroelectric polarization, piezoelectric response, and tunable optoelectronic properties. This review comprehensively examines how controlled structural distortions generate built‐in electric fields that overcome ultrafast charge ...
Xu Qian, Xinyu Li, Yihang Yu, Rayees Ahmad Rather, Christophe Colbeau‐Justin, Jingwei Li, Mohamed Nawfal Ghazzal   +6 more
wiley   +1 more source

Enantioselective synthesis and characterization of [<i>m</i>.<i>n</i>]paracyclophanes. [PDF]

Chem Sci
Wen Y, Yao Y, Zhong Y, Li C, Zhao C.
europepmc   +1 more source

Next‐Generation Carbon‐Based Anodes for Alkali Metal‐Ion Batteries: Recent Progress on Biphenylene and Emerging Materials

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Recent advances in carbon‐based anodes for alkali metal‐ion batteries are critically reviewed, with emphasis on biphenylene and other emerging carbon allotropes. Biphenylene exhibits exceptional theoretical electrochemical properties beyond conventional graphite, highlighting its strong potential as a next‐generation anode material once scalable ...
Adewale Hammed Pasanaje, Nirpendra Singh
wiley   +1 more source

A Practical and Scalable-Oriented Enantioselective Synthesis of (<i>S</i>)‑Autumnaline. [PDF]

Org Process Res Dev
Brusa A, Bottiglieri M, Tomassi C, Feola F, Lanaro D, Bonetti A, Zappia G, Sala F, Gambini A, Falzoni M, Allegrini P, Gelmi ML, Aschi M, Mazzanti A, Pesciaioli F, Carlone A.   +15 more
europepmc   +1 more source

Synthetic Strategies for the Construction of Cyclobutane‐Fused Heterocycles

European Journal of Organic Chemistry, EarlyView.
Cyclobutane‐fused heterocycles are important motifs commonly present in bioactive compounds, recognized for their rigid 3D structures that confer unique properties. However, synthesizing these compounds remains challenging. This review discusses current methods for their synthesis, such as photochemical, metal‐catalyzed, and Lewis acid‐mediated [2 + 2]
Michela Vargiu, Mauro Uras, Angelo Frongia   +2 more
wiley   +1 more source

Catalyst-controlled regiodivergence in enantioselective synthesis of spirocyclic γ- versus δ-lactams. [PDF]

Nat Commun
Wu SH, Gong F, Bi YB, Bai YZ, Zhong C, Cao Z, Deng QH.   +6 more
europepmc   +1 more source

Selective N‐Functionalization of Pyrazoles

European Journal of Organic Chemistry, EarlyView.
This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek, Matthias Schrader, Christopher J. Teskey   +2 more
wiley   +1 more source