Results 161 to 170 of about 14,649 (249)

Unified Enantioselective Synthesis of 5-Phenylmorphans and <i>cis</i>-Octahydroisoquinolines. [PDF]

Org Lett
Mahgoub AA, Khamrai J, Obakpolor O, Altman RA.   +3 more
europepmc   +1 more source

Enantioselective synthesis of C-C and C-N axially chiral pyrazole-based heterobiaryls. [PDF]

Chem Sci
He J, Yang Z, Lin L, Feng X.
europepmc   +1 more source

Enantioselective Synthesis of 3-Alkyl-1,5-Functionalized 1,4-Diynes via Isoxazol-5(4<i>H</i>)-ones. [PDF]

Org Lett
Torán R, Vercher S, López P, Sanz-Marco A, Montesinos-Magraner M, Vila C, Blay G.   +6 more
europepmc   +1 more source

Copper-catalyzed enantioselective synthesis of γ-butenolides via radical diversification of allenoic acid. [PDF]

Nat Commun
Han B, Nie Z, Ye C, Bao H.
europepmc   +1 more source

Barbituric Acids as Nucleophiles in Enantioselective Mannich Reactions: Organocatalytic Access to Quaternary Aminopyrazolone–Barbiturate Adducts

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
An enantioselective Mannich reaction using barbituric acids as nucleophiles provides access to chiral heterocycles bearing quaternary stereocenters. The transformation is catalyzed by a bifunctional thiourea with high selectivity. An immobilized catalyst enables recycling and application under continuous‐flow conditions, offering an efficient and ...
Rodrigo Sánchez‐Molpeceres, Mónica Llorente‐Pérez, Laura Martín, Alicia Maestro, José M. Andrés   +4 more
wiley   +1 more source

Ni-catalyzed enantioselective synthesis of β-aminoboronates via spin-center shift and proton transfer. [PDF]

Sci Adv
Wang Y, Wu G, Zhu W, Qi X, Song Q.
europepmc   +1 more source

Biocatalytic Application of Goodfellowiella coeruleoviolacea Imine Reductase: Enantioselective Synthesis of Cyclic Secondary Amines in Deep Eutectic Solvent‐Based Media

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A Goodfellowiella coeruleoviolacea Imine Reductase is here reported as a novel enzyme for biocatalytic application in chiral amine synthesis. Deep eutectic solvents have been used to increase substrate loadings, up to 150 mM, and boost enzymatic activity. Reaction scope and scale‐up procedure showcased the protocol applicability.
Federica De Nardi, Alessandro Marchetto, Nicoletta Schiavo, Francesca Spyrakis, Francesca Paradisi, Cristina Prandi   +5 more
wiley   +1 more source

Protein Language Model-Guided Engineering of a 2,3-Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α-Hydroxy Ketones. [PDF]

Adv Sci (Weinh)
Ding H, Jiang L, Song Y, Pu Z, Yang L, Yu H.   +5 more
europepmc   +1 more source

Synergistic Mechanism Between Ir–Phosphinito Catalyst and HFIP Enables Asymmetric Hydrogenation of Ketones Under Acidic Conditions

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A cooperative mechanism between a phosphinito Ir complex and HFIP provides a low‐energy pathway for hydrogen activation. This allowed the development of a highly efficient catalytic system for the hydrogenation of ketones that operates under acidic conditions, enabling the reduction of substrates containing phenols and carboxylic acids with no added ...
Martí Sidro, Agustí Lledós, María Vicent‐Morales, Jordi Benet‐Buchholz, Giuseppe Sciortino, Antoni Riera, Xavier Verdaguer   +6 more
wiley   +1 more source

Unveiling the migration reactivity of bicyclic diaziridines: enantioselective synthesis of chiral pyrazolines. [PDF]

Chem Sci
Liu Z, Ning L, Yang B, Wang K, Lin L, Feng X.   +5 more
europepmc   +1 more source