Results 181 to 190 of about 2,677,083 (277)

Enantioselective Synthesis of <i>cis</i>-Hydroisoquinolines via Cross-[4 + 2] Cycloadditions of 2‑Pyrones and Dihydropyridines. [PDF]

JACS Au
He JX, Lu QT, Tan K, Tian YY, Cai YQ, Topolovčan N, Cai Q.   +6 more
europepmc   +1 more source

DFT‐assisted rational design of salan ligands for highly enantioselective Zr–salan‐catalyzed hydroxylation of cyclic β‐keto esters

Smart Molecules, EarlyView.
Guided by DFT calculations, the design of novel C1‐symmetric salan ligands without the involvement of Suzuki coupling was achieved, and the preparation of α‐hydroxy‐β‐ketoesters in 99% yield and 99% ee was realized under low catalyst loading. Abstract In this work, a structurally simple, inexpensive, and readily accessible Zr–salan catalytic system was
Cunfei Ma, Kun Tang, Yuchen Jiang, Hongfei Zhu, Yufeng Wu, Yafeng Xing, Yakun Wang, Qilei Liu, Jian Du, Qingwei Meng   +9 more
wiley   +1 more source

Carbene-catalytic enantioselective synthesis of chiral macrocycles. [PDF]

Chem Sci
Yan H, Zhu Y, Yang G, Gu S.
europepmc   +1 more source

Modular Synthesis of α‐Quaternary Pyrrolines by Pyridoxal‐Catalyzed Sequential Reactions With Precise Chirality Relay

Transformative Chemistry, EarlyView.
Direct asymmetric α‐C conjugate addition of aminoacetonitrile enabled by carbonyl/iminium double activation, together with subsequent electrophilic functionalization, offers a one‐pot, two‐step modular strategy for synthesizing chiral α‐quaternary pyrrolines with precise chirality relay and high structural diversity.
Xingdie Yang, Pengwei Ji, Liang Liu, Tongyin Chen, Siqi Liu, Wen‐Wen Chen, Baoguo Zhao   +6 more
wiley   +1 more source

Catalytic enantioselective synthesis of alkylidenecyclopropanes. [PDF]

Nature
Golec JC, Tan DH, Yamazaki K, Tiekink EH, Christensen KE, Hamlin TA, Dixon DJ.   +6 more
europepmc   +1 more source

Electrochemical Reductive β‐Arylation and Alkenylation of α‐Branched Acroleins by Primary Amine/Nickel Dual Catalysis

Transformative Chemistry, EarlyView.
A synergistic primary amine/nickel catalysis under electrochemical conditions was developed for cathodic β‐arylation and alkenylation of α‐branched acroleins. The reaction proceeds through β‐enaminyl radicals generated by cathodic reduction of an iminium ion allowing smooth coupling with aryl‐ or alkenyl‐Ni(II) species.
Yingdong Duan, Fanzhu Zeng, Qifeng Lin, Sanzhong Luo   +3 more
wiley   +1 more source

Enantioselective synthesis of silicon-stereogenic sulfur-containing silanes <i>via</i> organocatalytic remote C-H sulfenylation of arenes. [PDF]

Chem Sci
Li SK, Zhang XY, Cai QY, Chu DR, Huo YX, Wang F, Gong XQ, Chen ZM.   +7 more
europepmc   +1 more source

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

The Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra, Subba Rao Cheekatla, Keshaba Nanda Parida   +2 more
wiley   +1 more source

A de‐novo Approach Towards Divergent [3+2π/σ] Photocycloadditions of Nitrones via Assembly‐Controlled Kinetic Electron Transfer Gating

Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.
A metal‐free photocatalytic platform converts nitrones into 4‐isoxazolines and oxa–aza–bicycloheptanes through divergent [3+2π/σ] cycloadditions. Assembly‐controlled kinetic electron transfer gating dictates substrate activation, enabling selective reactivity beyond thermodynamic expectations.
Nayan Saha, Rajesh Kancherla, Jorge Escorihuela, Shana Chandran, Mrinal K. Bera, Magnus Rueping, Burkhard König   +6 more
wiley   +2 more sources

Organocatalytic enantioselective synthesis and derivatizations of bridged <i>N</i>,<i>O</i>-acetal bicyclic scaffolds. [PDF]

Chem Sci
Tan J, Yusuipujiang N, Zhang J, Jiang XY, Zhang Z, Wang Y, Ma D.   +6 more
europepmc   +1 more source