Racemic dicyanotetrahelicene exhibits coverage‐dependent self‐assembly on Ag(111), transitioning from spontaneous chiral resolution at low coverage to a dense mixed phase at monolayer saturation. While submonolayer deposition produces extended homochiral domains, full coverage yields a compact, long‐range ordered lattice with an enantiomerically ...
Aleksandra Cebrat +5 more
wiley +1 more source
Correction to "Enantioselective Synthesis of 2,3-Disubstituted Azetidines via Copper-Catalyzed Boryl Allylation of Azetines". [PDF]
Zhu M, Sun J.
europepmc +1 more source
Spin Effects in Photocatalysis: Fundamental Insights and Applications
This review outlines the fundamental principles of spin‐dependent processes in photocatalysis, with a focus on recent advances in spin effects across various applications, including photocatalytic water splitting, CO2 conversion, environmental remediation, organic synthesis, and H2O2 production.
Yang‐Sen Xu +4 more
wiley +1 more source
Overriding Stereochemical Outcomes in Cyclase Phase Total Synthesis: Enantioselective Synthesis of Habiterpenol and Dasyscyphin A. [PDF]
Wu L +5 more
europepmc +1 more source
Machine Learning Approaches for GC–MS Data Interpretation in Flavour and Fragrance Analysis
The review explores machine learning integration in GC‐MS data analysis for the fragrance and flavour industry, highlighting recent advances and techniques in a context constrained by data scarcity and intellectual property concerns. ABSTRACT This review explores the integration of machine learning (ML) in the analysis of mass spectrometry data ...
Jean‐Baptiste Coffin +3 more
wiley +1 more source
Photoenzymatic Hydroalkylation Enables Streamlined Access to Aryl Glutarimide Precursors
We report a photoenzymatic hydroalkylation that enables streamlined, stereocontrolled access to aryl glutarimide precursors relevant to targeted protein degradation. Engineered flavin‐dependent “ene”‐reductases provide broad scope and high enantioselectivity through a distinct electron transfer–enantioselective proton transfer pathway.
Zhi Xu +9 more
wiley +2 more sources
Catalytic enantioselective synthesis of selenium-containing atropisomers via C-Se bond formations. [PDF]
Gao QS, Wei ZW, Chen ZM.
europepmc +1 more source
Rhodium‐Catalyzed Regioselective Addition of N‐Hydroxyl Imides to Internal Alkynes
An intermolecular rhodium‐catalyzed regioselective addition of N‐hydroxyl imides to internal alkynes leads to branched O‐allyl compounds, which can be readily transformed to allylic alcohols and O‐allyl hydroxylamines after deprotection. Isotopic labelling experiments suggest a plausible reaction mechanism.
Zi Liu, Bernhard Breit
wiley +1 more source
Biocatalytic kinetic resolution for efficient and enantioselective synthesis of δ-haloalcohols and tetrahydrofurans. [PDF]
Wang YF +6 more
europepmc +1 more source
Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang +6 more
wiley +1 more source

