Results 281 to 290 of about 3,273,294 (390)

Identification of Key Active‐Site Positions Controlling the Chemoselectivity of Aspergillus Brasiliensis Unspecific Peroxygenase

ChemBioChem, EarlyView.
Unspecific peroxygenase (UPO) from Aspergillus brasiliensis AbrUPO catalyzes the aromatic hydroxylation of substituted benzenes. By integrating structural elements from well‐characterized UPOs in AbrUPO variants, position 186 was identified as a critical determinant of enzyme chemoselectivity.
Fabian Schmitz, Maike Hoffrogge, Katja Koschorreck, Yasuhisa Fukuta, Alessandra Raffaele, Florian Tieves, Thomas Hilberath, Frank Hollmann, Vlada B. Urlacher   +8 more
wiley   +1 more source

Organocatalytic skeletal reorganization for enantioselective synthesis of S-stereogenic sulfinamides. [PDF]

Nat Commun
Liu Z, Fang S, Li H, Xiao C, Xiao K, Su Z, Wang T.   +6 more
europepmc   +1 more source

Enantioselective Synthesis of the Key Intermediate of the Acyl-CoA. Cholesterol Acyltransferase (ACAT) Inhibitor (R-106578) Using 2,2'-Bis(diphenylphosphino)-1,1'-binaphthyl (BINAP)-Ru(OAc)2 as a Catalyst.

, 2000
Masayuki Murakami, Keijiro Kobayashi, Koichi Hirai   +2 more
openalex   +2 more sources

An Indole Dearomatization Strategy for the Synthesis of Pseudo‐Natural Products

ChemBioChem, EarlyView.
An indole‐dearomatization/reduction strategy is developed to expand a collection of indole‐containing pseudo‐NPs. This approach enhances the three‐dimensionality of the original compound classes through hybridization‐changing conversions leading to topologically distinct novel structures.
Joseph G. F. Hoock, Annina Burhop, Luca C. Greiner, Beate Schölermann, Celine Da Cruz Lopes Guita, Jie Liu, Sukdev Bag, Axel Pahl, Sonja Sievers, Rebecca Scheel, Carsten Strohmann, Slava Ziegler, Michael Grigalunas, Herbert Waldmann   +13 more
wiley   +1 more source

Highly Enantioselective Synthesis of 3,3-Diarylpropyl Amines and 4-Aryl Tetrahydroquinolines via Ir-Catalyzed Asymmetric Hydrogenation. [PDF]

Org Lett
Sidro M, García-Mateos C, Rojo P, Wen Y, Riera A, Verdaguer X.   +5 more
europepmc   +1 more source

Enantioselective synthesis of a cyclopentannulated kalafungin analogue

, 2000
Margaret A. Brimble, John McEwan
openalex   +2 more sources

Diversity Of ThDP‐Dependent Enzymes Forming Chiral Tertiary Alcohols

ChemBioChem, Accepted Article.
Thiamine diphosphate (ThDP)‐dependent enzymes are well known biocatalysts for C−C bond‐forming reactions. While this enzyme class is mainly investigated for the formation of acyloins of secondary alcohols, recent studies have expanded its scope to utilize ketones as electrophiles in asymmetric carboligation reactions for the formation of tertiary ...
Daniela Bjarnesen, Lucrezia Lanza, Francesco Presini, Pier Paolo Giovannini, Michael Müller   +4 more
wiley   +1 more source

Synthesis, Resolution and Use in Enantioselective Catalysis of an Axially Chiral Binaphthyl-templated P,S-heterodonor Ligand (binaps)

, 2000
Serafino Gladiali, Serenella Medici, Giovanna Pirri, Sonia Pulacchini   +3 more
openalex   +1 more source

Enantioselective synthesis of γ-chiral amides via copper-catalyzed reductive relay hydroaminocarbonylation. [PDF]

Nat Commun
Yuan Y, Zhang Y, Wu XF.
europepmc   +1 more source

Enantioselective Synthesis of 2- and 3-Benzofuryl b-Amino Alcohols

, 2001
M. Zaidlewicz, Aldona Chechłowska, A. Prewysz‐Kwinto, Andrzej Wojtczak   +3 more
openalex   +1 more source