Results 331 to 340 of about 3,273,294 (390)

Organocatalytic Enantioselective Synthesis of Axially Chiral N,N'-Bisindoles.

Angewandte Chemie, 2023
This study establishes the first organocatalytic enantioselective synthesis of axially chiral N,N'-bisindoles via chiral phosphoric acid-catalyzed formal (3+2) cycloadditions of indole-based enaminones as novel platform molecules with 2,3-diketoesters ...
Zhihua Chen   +6 more
semanticscholar   +1 more source

Enantioselective Synthesis of N-N Bisindole Atropisomers.

Angewandte Chemie, 2022
N-N Atropisomers are a common motif in natural products and represent a significant dimension for exploration in modern pharmaceutical and medicinal chemistry.
Peng Zhang   +6 more
semanticscholar   +1 more source

Catalytic Enantioselective Synthesis of Helicenes.

Chemistry, 2022
Helicenes and helicene-like molecules, usually containing multiple ortho -fused aromatic rings, possess unique helical chirality. These compounds have found a wide range of important applications in many research fields, such as asymmetric catalysis ...
W. Liu   +3 more
semanticscholar   +1 more source

Enantioselective Synthesis of Nitrogen-Nitrogen Biaryl Atropisomers via Copper-Catalyzed Friedel-Crafts Alkylation Reaction.

Journal of the American Chemical Society, 2021
Nitrogen-nitrogen bonds containing motifs are ubiquitous in natural products and bioactive compounds. However, the atropisomerism arising from a restricted rotation around an N-N bond is largely overlooked.
Xiao‐Mei Wang   +6 more
semanticscholar   +1 more source

Enantioselective Synthesis of Atropisomeric Biaryls by Pd-Catalyzed Asymmetric Buchwald-Hartwig Amination.

Angewandte Chemie, 2021
N-C Biaryl atropisomers are important because of their prevalence in natural products and bioactive drug molecules. However, the enantioselective synthesis of such molecules has not developed significantly. Particularly, the enantioselective synthesis of
Peng Zhang   +6 more
semanticscholar   +1 more source

Recent advances in organocatalytic asymmetric multicomponent cascade reactions for enantioselective synthesis of spirooxindoles

Organic Chemistry Frontiers, 2021
Catalytic asymmetric MCCRs for enantioselective synthesis of spirooxindoles by using chiral phosphoric acids, amines, bifunctional thiourea/squaramides and metal-based reagents as catalysts.
Yongchao Wang, Angel A. Cobo, A. Franz
semanticscholar   +1 more source

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