Results 201 to 210 of about 26,170 (225)
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Endocannabinoid System and the Otolaryngologist
Otolaryngologic Clinics of North America, 2022The endocannabinoid system is located throughout the central and peripheral nervous systems, endocrine system, gastrointestinal system, and within inflammatory cells. The use of medical cannabinoids has been gaining traction as a viable treatment option for varying illnesses in recent years. Research is ongoing looking at the effect of cannabinoids for
Brandon, Tapasak +2 more
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2017
The endocannabinoid system was only discovered about 25 years ago, but it is now known to be a major modulator of synaptic activity throughout the brain. CB1 receptors are located on presynaptic terminals of neurons that release other neurotransmitters and the action of agonists of these receptors is to turn-off neurotransmitter release.
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The endocannabinoid system was only discovered about 25 years ago, but it is now known to be a major modulator of synaptic activity throughout the brain. CB1 receptors are located on presynaptic terminals of neurons that release other neurotransmitters and the action of agonists of these receptors is to turn-off neurotransmitter release.
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The endocannabinoid system in invertebrates
Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA), 2002What is the role of the cannabinoid system in invertebrates and can it tell us something about the human system? We discuss in this review the possible presence of the cannabinoid system in invertebrates. Endocannabinoid processes, i.e., enzymatic hydrolysis, as well as cannabinoid receptors and endocannabinoids, have been identified in various species
M, Salzet, G B, Stefano
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Review of the Endocannabinoid System
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2021The endocannabinoid system (ECS) is a widespread neuromodulatory network involved in the developing central nervous system as well as playing a major role in tuning many cognitive and physiological processes. The ECS is composed of endogenous cannabinoids, cannabinoid receptors, and the enzymes responsible for the synthesis and degradation of ...
Hui-Chen, Lu, Ken, Mackie
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Cutaneous Endocannabinoid System
2012Endocannabinoids (ECS) constitute lipid mediators (amides, esters, and ethers of long chain polyunsaturated fatty acids) which act similarly to the exogenous Δ9 tetrahydrocannabinol (THC; the main psychoactive ingredient of the plant Cannabis sativa) and are produced in humans and animals (Maccarrone et al. 2003; Rahn and Hohmann 2009).
Andrzej T. Slominski +5 more
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Endocannabinoid System and Cardiometabolic Risk
Clinical Pharmacology & Therapeutics, 2007The increasing prevalence of overweight and obesity counteracts the favorable advances of risk factor management achieved for cardiovascular disease (CVD) prevention. Obese and overweight individuals are at increased risk for CVDs and diabetes mellitus, a risk pattern called "cardiometabolic risk." There is a growing interest concerning the role of the
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Biology of endocannabinoid synthesis system
Prostaglandins & Other Lipid Mediators, 2009Endocannabinoids (endogenous ligands of cannabinoid receptors) exert diverse physiological and pathophysiological functions in animal tissues. N-Arachidonoylethanolamine (anandamide) and 2-arachidonoylglycerol (2-AG) are two representative endocannabinoids.
Jun, Wang, Natsuo, Ueda
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Endocannabinoid Regulation of Neuroendocrine Systems
2015The hypothalamus is a part of the brain that is critical for sustaining life through its homeostatic control and integrative regulation of the autonomic nervous system and neuroendocrine systems. Neuroendocrine function in mammals is mediated mainly through the control of pituitary hormone secretion by diverse neuroendocrine cell groups in the ...
Jeffrey G, Tasker +5 more
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The endocannabinoid system and migraine
Experimental Neurology, 2010The recently discovered endocannabinoid system (ECS), which includes endocannabinoids and the proteins that metabolize and bind them, has been implicated in multiple regulatory functions both in health and disease. Several studies have suggested that ECS is centrally and peripherally involved in the processing of pain signals.
GRECO R +3 more
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Endocannabinoid System in Neurological Disorders
Recent Patents on CNS Drug Discovery, 2016Several studies support the evidence that the endocannabinoid system and cannabimimetic drugs might have therapeutic potential in numerous pathologies. These pathologies range from neurological disorders, atherosclerosis, stroke, cancer to obesity/metabolic syndrome and others.In this paper we review the endocannabinoid system signaling and its ...
Ranieri R. +4 more
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