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The influence of genetics on the endocannabinoid system gene expression and relevance for targeting reproductive conditions. [PDF]
Tanaka K +8 more
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Role of the Endocannabinoid System in Fibromyalgia. [PDF]
García-Domínguez M.
europepmc +1 more source
Corticosterone stimulates synthesis of 2-arachidonoylglycerol via putative membrane-bound glucocorticoid receptors and inhibits GABA release via CB1 cannabinoid receptors in the ventrolateral periaqueductal gray. [PDF]
Coutens B +6 more
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Česká gynekologie, 2021
Objective: Overview of current knowledge in the field of the endocannabinoid system with emphasis on the relationships between endocannabinoids and exocannabinoids. The endocannabinoid system consists of cannabinoid receptors 1 and 2, ligands of these receptors, especially two "classical" endocannabinoids N-arachidonoylethanolamine (anandamide) and 2 ...
Josef, Suchopár +4 more
openaire +2 more sources
Objective: Overview of current knowledge in the field of the endocannabinoid system with emphasis on the relationships between endocannabinoids and exocannabinoids. The endocannabinoid system consists of cannabinoid receptors 1 and 2, ligands of these receptors, especially two "classical" endocannabinoids N-arachidonoylethanolamine (anandamide) and 2 ...
Josef, Suchopár +4 more
openaire +2 more sources
European Journal of Pharmacology, 1998
The background knowledge leading to the isolation and identification of anandamide and 2-arachidonoyl glycerol, the principal endocannabinoids is described. The structure-activity relationships of these lipid derivatives are summarized. Selected biochemical and pharmacological topics in this field are discussed, the main ones being levels of ...
R, Mechoulam, E, Fride, V, Di Marzo
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The background knowledge leading to the isolation and identification of anandamide and 2-arachidonoyl glycerol, the principal endocannabinoids is described. The structure-activity relationships of these lipid derivatives are summarized. Selected biochemical and pharmacological topics in this field are discussed, the main ones being levels of ...
R, Mechoulam, E, Fride, V, Di Marzo
openaire +2 more sources
From endocannabinoid profiling to ‘endocannabinoid therapeutics’
Current Opinion in Chemical Biology, 2009The discovery of the endocannabinoid signalling system, that is, of cannabinoid receptors, their endogenous ligands, known as endocannabinoids, and of endocannabinoid anabolic and catabolic enzymes, raised several questions regarding the physiopathological role of these mediators. Several of these questions were answered by investigating alterations in
Ligresti A, Petrosino S, Di Marzo V
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