Results 171 to 180 of about 2,670,563 (294)

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Endocrine Controls of Skin Aging

Skin is the largest organ of the human body and undergoes both intrinsic (chronological) and extrinsic aging. While intrinsic skin aging is driven by genetic and epigenetic factors, extrinsic aging is mediated by external threats such as UV irradiation ...
Stegemann, Agatha, Böhm, Markus, Maity, Pallab, Kleszczyński, Konrad, Scharffetter-Kochanek, Karin, Paus, Ralf, Wlaschek, Meinhard   +6 more
core   +1 more source

SERENA-6 interpretation and clinical implications: intercepting endocrine resistance in metastatic breast cancer. [PDF]

NPJ Breast Cancer
Bidard FC, Barrios C, Bianchini G, Brufsky AM, Chia S, Cortes J, Cristofanilli M, Curigliano G, Dawood S, Fasching PA, Gerratana L, Giordano A, Ignatiadis M, Iwata H, Janni W, Lim E, Kalinsky K, Ma CX, Mayer EL, Medford AJ, Mouabbi JA, O'Shaughnessy J, Park YH, Pascual J, Razavi P, Sammons S, Sandoval JL, Sisca L, Tarantino P, Wander SA, Werutsky G, Turner NA.   +31 more
europepmc   +1 more source

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

ICAM2 promotes endocrine resistance via dynein-mediated OXPHOS activation in ER-positive breast cancer. [PDF]

Cell Death Dis
Chen S, Wu S, Hu J, Liu B, Liu Y, Yang S, Tang F, He Y, Liu Q, Liu Y, Du Y, Zhang G, Guo Q, Gao F, Yang C.   +14 more
europepmc   +1 more source

Correlation between serum lipid levels and endocrine resistance in patients with ER-positive breast cancer. [PDF]

Medicine (Baltimore), 2023
Sun H, Hu C, Zheng X, Zhuang J, Wei X, Cai J.   +5 more
europepmc   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

Advanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen, Hongdou Shen, Weiyue Wu, Zhuoying Jiang, Bin Liu, Yansi Xian, Rui Peng, An Yan, Yu Ben, Yong Shi, Xiang Chen, Baosheng Guo, Qing Jiang, Weijun Wang, Pingqiang Cai   +14 more
wiley   +1 more source

Human Cytomegalovirus Suppresses Estrogen and Progesterone Receptor Expression in Hormone Receptor-Positive Breast Cancer Cells: Implications for Endocrine Resistance. [PDF]

Cancers (Basel)
Garcia EC, LaRue IJ, Griggs ND, Spencer JV.   +3 more
europepmc   +1 more source

Endocrine resistance and breast cancer plasticity are controlled by CoREST. [PDF]

Nat Struct Mol Biol, 2022
Garcia-Martinez L, Adams AM, Chan HL, Nakata Y, Weich N, Stransky S, Zhang Z, Alshalalfa M, Sarria L, Mahal BA, Kesmodel SB, Celià-Terrassa T, Liu Z, Minucci S, Bilbao D, Sidoli S, Verdun RE, Morey L.   +17 more
europepmc   +1 more source