Results 41 to 50 of about 2,670,563 (294)
Communications Biology, 2023 Endocrine resistance is a major challenge for breast cancer therapy. To identify the genes pivotal for endocrine-resistance progression, we screened five datasets and found 7 commonly dysregulated genes in endocrine-resistant breast cancer cells. Here we
Jing Zhou +6 more
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Frontiers in Pharmacology, 2021 Background: Lactate dehydrogenase (LDH) plays an important role in cancer pathogenesis and enhanced expression/activity of this enzyme has been correlated with poor prognosis. In this study we determined the expression profile of LDH-A and B in normal as
Maitham A. Khajah +2 more
doaj +1 more source
, 2015 This Executive Summary to the Endocrine Society's second Scientific Statement on environmental endocrine-disrupting chemicals (EDCs) provides a synthesis of the key points of the complete statement.
Prins, Gail S., +7 more
core +1 more source
Microarray analysis of tamoxifen resistance in breast cancer. [PDF]
, 2009 PhDTamoxifen remains a widely used hormone therapy for pre and postmenopausal women with hormone receptor positive breast cancer in both adjuvant and metastatic disease settings. Resistance to this well tolerated and cost-effective drug limits its use.
Moss, Charlotte
core +4 more sources
ARID1A Mutation in Metastatic Breast Cancer: A Potential Therapeutic Target
Frontiers in Oncology, 2021 Distant metastasis is the principal cause of mortality for breast cancer patients. Targeting specific mutations that have been acquired during the evolution process of advanced breast cancer is a potential means of enhancing the clinical efficacy of ...
Xuan Cheng +13 more
doaj +1 more source
Non-canonical Estrogen Signaling in Endocrine Resistance [PDF]
Frontiers in Endocrinology, 2019 Breast cancer is one of the leading causes of cancer related deaths in women worldwide. The disease is extremely heterogenous. A large percentage of the breast cancers are dependent on estrogen signaling and hence respond to endocrine therapies which essentially block the estrogen signaling.
Prathibha Ranganathan +2 more
openaire +3 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
EDC-2 : The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
, 2015 The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to the scientific community about how environmental endocrine-disrupting chemicals (EDCs) affect health and disease.
Prins, Gail S., +7 more
core +1 more source
Endocrine disruption in juvenile roach from English rivers: A preliminary study [PDF]
, 2004 Juvenile roach Rutilus rutilus from seven rivers of varying water quality were examined for evidence of endocrine disruption. The majority of roach from five of these rivers had femalelike reproductive ducts.
Williams, R +3 more
core +1 more source
Frontiers in Oncology, 2020 Introduction: Mutations in the ESR1 gene (ESR1m) are important mechanisms of resistance to endocrine therapy in estrogen receptor–positive (ER+) metastatic breast cancer and have been studied as a potential therapeutic target, as well as a predictive and
Tomás Reinert +17 more
doaj +1 more source