Results 241 to 250 of about 342,266 (343)

Neutrophil Macrophage Crosstalk via Extracellular Vesicles Drives Reverse Migration in a Fully Human Model of Wound Healing

Advanced Science, EarlyView.
A novel microphysiological system that can mimic sterile or non‐sterile injury demonstrates that macrophage‐derived extracellular vesicles modulate neutrophil migratory responses to these different wound states. The model showed that resolution of inflammation through neutrophil reverse migration is driven by IL‐8 derived from extracellular vesicles ...
Kehinde Adebayo Babatunde, Oluwadamilola Fatimat Babatunde, Adeel Ahmed, Wilmara Salgado‐Pabon, David J Beebe, Sheena C. Kerr   +5 more
wiley   +1 more source

DNAJC5 facilitates the proliferation and migration of lung adenocarcinoma cells by augmenting EGFR trafficking. [PDF]

Commun Biol
Chen C, Xu L, Chen L, Zhai Z, Cheng M, Luo S, Wang H.   +6 more
europepmc   +1 more source

Kindlin Regulates Mechanosensitive Activation and Adhesion Assembly of Integrin beta6

Advanced Science, EarlyView.
Extracellular matrix compliance plays a critical role in the regulation of integrin‐mediated adhesion and cell motility. Here, it is reported that strengthening the kindlin2‐integrin β6 interaction overcomes the dependence on extracellular substrate stiffness and promotes integrin β6‐mediated cell migration.
Wan Ning Lee, Jiamin Li, Nan‐Peng Chen, Cheng‐han Yu   +3 more
wiley   +1 more source

Retraction for Austin et al., Death-receptor activation halts clathrin-dependent endocytosis. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Brassinosteroid Signaling Dynamics: Ubiquitination-Dependent Regulation of Core Signaling Components. [PDF]

Int J Mol Sci
Qiu R, Zhou Y, Mao J.
europepmc   +1 more source

Remodeling the Physicochemical and Pharmacokinetic Properties of PROTAC via Lipid Nanodisks for Cancer Therapy

Advanced Science, EarlyView.
To solve the challenge of PROTACs in clinical potential due to poor water solubility and membrane permeability, a nanodelivery system based on lipid nanodisks loaded with MZ1 prodrug (LND‐MZ1) to remodel the physicochemical and pharmacokinetic properties of PROTAC MZ1 is elaborately proposed.
Meichen Pan, Chunrong Yang, Zhongliang Fu, Yuchen Yang, Ying Zhuo, Hongwei Hou, Jinghong Li   +6 more
wiley   +1 more source

α-Synuclein interacts directly with AP2 and regulates its binding to synaptic membranes. [PDF]

J Biol Chem
Vargas KJ, Wallace JN, Mooney I, Owen DJ, Morgan JR.   +4 more
europepmc   +1 more source

Independence of type I angiotensin II receptor endocytosis from G protein coupling and signal transduction.

, 1994
László Hunyady, Albert J. Baukal, Tamás Balla, Kevin Catt   +3 more
openalex   +1 more source

Molecules internalized by clathrin-independent endocytosis are delivered to endosomes containing transferrin receptors. [PDF]

, 1993
Steen H. Hansen, Kirsten Sandvig, Bo van Deurs   +2 more
openalex   +1 more source

Harnessing the Immunomodulation of UV‐Exposed Keratinocyte Extracellular Vesicles for Inflammatory Disorder Treatment

Advanced Science, EarlyView.
Adopting a paradigm shift that transforms a known health hazard as a potential therapeutic asset, a novel therapeutic strategy is set out to investigate for inflammatory conditions by leveraging immunosuppressive properties of UV‐irradiated keratinocytes.
Lu Liu, Ding Yang, Jingsen Ji, Gengyou Li, Haoting Chen, Yuying Yao, Chenxing Fu, Fangling Liao, Jinzhao Liu, Yaming Zhang, Zechuan Li, Jing Zhang, Huike Ma, Jingxia Zhao, Ying‐Shi Sun, Weisheng Guo, Weiping Wang   +16 more
wiley   +1 more source