Results 81 to 90 of about 342,266 (343)

Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plamsa membrane [PDF]

, 2008
Hemochromatosis type 2 gene (HFE2) is highly expressed in skeletal muscle and liver hepatocytes. Its encoded protein, hemojuvelin (HJV), is a co-receptor for the bone morphogenetic proteins 2 and 4 (BMP2 and BMP4) and enhances the BMP-induced hepcidin ...
Altschuler, Babitt, Babitt, Bowman, Camaschella, Chadda, Cole, De Gobbi, Feng, Hammond, Hentze, Huang, Keeling, Krijt, Kuninger, Lin, Lin, Lin, Macia, Matsunaga, Mawdsley, Mayor, Mayor, Meyerhardt, Nemeth, Nichols, Niederkofler, Niederkofler, Oldekamp, Orlandi, Papanikolaou, Park, Pigeon, Roy, Samad, Schmidt, Schmidtmer, Silvestri, Silvestri, Subtil, ten Dijke, Thomas, VanSlyke, Vielmetter, Wang, Wilson, Wilson, Wilson, Yang, Zhang, Zhang, Zhang   +51 more
core   +3 more sources

Flowers for Synaptic Endocytosis [PDF]

Cell, 2009
Exocytosis and endocytosis of synaptic vesicles are tightly coordinated to maintain a steady supply of new vesicles during periods of extended neuronal stimulation. Yao et al. (2009) now report that a synaptic vesicle membrane protein named Flower promotes endocytosis at neuromuscular junctions in the fruit fly Drosophila.
Brose, Nils, Neher, Erwin
openaire   +4 more sources

Endocytosis of Bacteriophages

Current Opinion in Virology, 2022
Endocytosis is used by eukaryotic cells for ingesting external objects. Importantly, endocytosis is a major process that determines phage pharmacokinetics in vivo. Either dissemination of phages throughout the system or phage clearance engages cellular uptake of phage particles.
Paulina Miernikiewicz, Krystyna Dąbrowska   +1 more
openaire   +2 more sources

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

Importance of Endocytosis for the Biological Activity of Cedar Virus Fusion Protein

Cells, 2020
Endocytosis plays a particular role in the proteolytic activation of highly pathogenic henipaviruses Hendra (HeV) and Nipah virus (NiV) fusion (F) protein precursors. These proteins require endocytic uptake from the cell surface to be cleaved by cellular
Kerstin Fischer, Martin H. Groschup, Sandra Diederich   +2 more
doaj   +1 more source

Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]

, 2012
Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Albert, AP, Lawrence, KM, Stenbeck, G
core   +2 more sources

Endocytosis and Signaling [PDF]

Cell, 2001
Far from being a simple attenuator, endocytosis is now also implicated in the initiation and propagation of signals. Signaling reciprocates by controlling endocytosis and contributing to its ability to selectively sort receptors. It appears that the quiet days of endocytosis as a relatively “stand-alone” process are over, as we expose the intricate ...
PP. Di Fiore, P. De Camilli
openaire   +3 more sources

Pathway Analyses of Inherited Neuropathies Identify Putative Common Mechanisms of Axon Degeneration

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Inherited neuropathies (IN) are associated with over 100 different genetic mutations presenting with a variety of phenotypes. This complexity suggests multiple pathways may converge onto a limited number of downstream pathways to effect axonal injury.
Christopher R. Cashman, Craig Blackstone, Reza Sadjadi   +2 more
wiley   +1 more source

Endocytic Adaptors in Cardiovascular Disease

Frontiers in Cell and Developmental Biology, 2020
Endocytosis is the process of actively transporting materials into a cell by membrane engulfment. Traditionally, endocytosis was divided into three forms: phagocytosis (cell eating), pinocytosis (cell drinking), and the more selective receptor-mediated ...
Kui Cui, Kui Cui, Yunzhou Dong, Yunzhou Dong, Beibei Wang, Beibei Wang, Douglas B. Cowan, Douglas B. Cowan, Douglas B. Cowan, Siu-Lung Chan, Siu-Lung Chan, John Shyy, Hong Chen, Hong Chen   +13 more
doaj   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source