Results 11 to 20 of about 603,777 (298)
Endogenous Retroviruses in Nervous System Disorders [PDF]
Pharmaceuticals, 2021 Human endogenous retroviruses (HERV) have been implicated in the pathogenesis of several nervous system disorders including multiple sclerosis and amyotrophic lateral sclerosis.
Victoria Gröger +3 more
doaj +5 more sources
Human-Specific Endogenous Retroviruses [PDF]
The Scientific World Journal, 2007 This review focuses on a small family of human-specific genomic repetitive elements, presented by 134 members that shaped ~330 kb of the human DNA. Although modest in terms of its copy number, this group appeared to modify the human genome activity by ...
Anton Buzdin
doaj +3 more sources
Cellular and Molecular Life Sciences, 2008 Sheep betaretroviruses offer a unique model system to study the complex interaction between retroviruses and their host. Jaagsiekte sheep retrovirus (JSRV) is a pathogenic exogenous retrovirus and the causative agent of ovine pulmonary adenocarcinoma.
K. Ruprecht +4 more
+14 more sources
Switching Sides: How Endogenous Retroviruses Protect Us from Viral Infections
Journal of Virology, 2021 Long disregarded as junk DNA or genomic dark matter, endogenous retroviruses (ERVs) have turned out to represent important components of the antiviral immune response.
Smitha Srinivasachar Badarinarayan +1 more
semanticscholar +3 more sources
Human Endogenous Retroviruses in Glioblastoma Multiforme
Microorganisms, 2021 Glioblastoma multiforme (GBM) is the most aggressive and deadly brain tumor. It is primarily diagnosed in the elderly and has a 5-year survival rate of less than 6% even with the most aggressive therapies.
Zihao Yuan +6 more
doaj +2 more sources
The discovery of endogenous retroviruses [PDF]
Retrovirology, 2006 When endogenous retroviruses (ERV) were discovered in the late 1960s, the Mendelian inheritance of retroviral genomes by their hosts was an entirely new concept.
Weiss Robin A
doaj +4 more sources
Endogenous retroviruses mediate transcriptional rewiring in response to oncogenic signaling in colorectal cancer [PDF]
bioRxiv, 2021 Cancer cells exhibit rewired transcriptional regulatory networks that promote tumor growth and survival. However, the mechanisms underlying the formation of these pathological networks remain poorly understood.
A. Ivancevic +7 more
semanticscholar +2 more sources
Human endogenous retroviruses and cancer
Cancer Biology & Medicine, 2016 Human endogenous retroviruses (HERVs) are retroviruses that infected human genome millions of years ago and have persisted throughout human evolution.
María Gonzalez-Cao +5 more
doaj +4 more sources
Endogenous retroviruses are dysregulated in ALS [PDF]
iScienceSummary: Amyotrophic lateral sclerosis (ALS) is a universally fatal neurodegenerative disease with no cure. Human endogenous retroviruses (HERVs) have been implicated in its pathogenesis but their relevance to ALS is not fully understood.
Nicholas Pasternack +4 more
doaj +2 more sources
Human endogenous retroviruses and exogenous viral infections [PDF]
Frontiers in Cellular and Infection MicrobiologyThe human genome harbors many endogenous retroviral elements, known as human endogenous retroviruses (HERVs), which have been integrated into the genome during evolution due to infections by exogenous retroviruses.
Chenxuan Bao +9 more
doaj +2 more sources