Results 51 to 60 of about 13,041 (209)
Biomedicines, 2022 Angiogenesis is the process of vascular network development and plays a crucial role in cancer growth, progression, and metastasis. Phthalates are a class of environmental pollutants that have detrimental effects on human health and are reported to ...
Mahendra Jadhao +10 more
doaj +1 more source
Effect of antihypertensive therapy with alpha methyldopa on levels of angiogenic factors in pregnancies with hypertensive disorders. [PDF]
, 2008 Antihypertensive drugs are believed to lower blood pressure in pre-eclampsia by direct or central vasodilatory mechanisms. However, they could also act by decreasing production of anti-angiogenic proteins involved in the pathophysiology of hypertension ...
Muttukrishna Shanthi +11 more
core +1 more source
Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin [PDF]
Circulation Research, 2010 Rationale : Arteriovenous malformations (AVMs) result in anomalous direct blood flow between arteries and veins, bypassing the normal capillary bed. Depending on size and location, AVMs may lead to severe clinical effects including systemic cyanosis ...
Mahmoud M +7 more
openaire +3 more sources
Endoglin Protein Interactome Profiling Identifies TRIM21 and Galectin-3 as New Binding Partners
Cells, 2019 Endoglin is a 180-kDa glycoprotein receptor primarily expressed by the vascular endothelium and involved in cardiovascular disease and cancer. Heterozygous mutations in the endoglin gene (ENG) cause hereditary hemorrhagic telangiectasia type 1, a ...
Eunate Gallardo-Vara +7 more
doaj +1 more source
A Phase II Trial of Perioperative Oral Itraconazole for the Management of Low-Risk Basal Cell Carcinoma. [PDF]
Exp DermatolNeoadjuvant treatment with oral itraconazole for two months demonstrated significant responses in low‐risk basal cell carcinomas. This effect was associated with decreased tumour angiogenesis, presenting a favourable safety profile for patients. ABSTRACT Recently, new treatment strategies have been developed for advanced or metastatic basal cell ...
Pereira RP +7 more
europepmc +2 more sources
L-Endoglin overexpression increases renal fibrosis after unilateral ureteral obstruction. [PDF]
PLoS ONE, 2014 Transforming growth factor-β (TGF-β) plays a pivotal role in renal fibrosis. Endoglin, a 180 KDa membrane glycoprotein, is a TGF-β co-receptor overexpressed in several models of chronic kidney disease, but its function in renal fibrosis remains uncertain.
Bárbara Oujo +11 more
doaj +1 more source
Marine silicon for biomedical sustainability
BMEMat, EarlyView.Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han +3 more
wiley +1 more source
Running head: Endoglin isoforms in myeloid cells [PDF]
, 2015 40 p.-7 fig.-1 tab.Endoglin is an auxiliary cell surface receptor for TGF-beta family members. Two different alternatively spliced isoforms, long (L)-endoglin and short (S)-endoglin, have been reported.
Benguria, Alberto +17 more
core +1 more source
Expression of endoglin (CD105) in cervical cancer [PDF]
British Journal of Cancer, 2009 In this study, we have investigated the role of endoglin (CD105), a regulator of transforming growth factor (TGF)-beta(1) signalling on endothelial cells, basic fibroblast growth factor (bFGF) and vascular endothelial growth factor-A (VEGF-A) in cervical cancer.
Zijlmans, H. J. +6 more
openaire +3 more sources
Mice Lacking Endoglin in Macrophages Show an Impaired Immune Response.
PLoS Genetics, 2016 Endoglin is an auxiliary receptor for members of the TGF-β superfamily and plays an important role in the homeostasis of the vessel wall. Mutations in endoglin gene (ENG) or in the closely related TGF-β receptor type I ACVRL1/ALK1 are responsible for a ...
Luisa Ojeda-Fernández +11 more
doaj +1 more source