Results 31 to 40 of about 9,267 (204)
Development of cochlear spiral ligament fibrocytes of the common marmoset, a nonhuman model animal
Scientific Reports, 2023 Spiral ligament fibrocytes generate potassium gradients, which hair cells require to convert mechanical sound waves into electrical palsy. Together with the stria vascularis, they regulate endolymph electrolyte homeostasis.
Makoto Hosoya +6 more
doaj +1 more source
Endolymph Composition: Paradigm or Inevitability?
Physiological Research, 2018 This review is focused on the unusual composition of the endolymph of the inner ear and its function in mechanoelectrical transduction. The role of K+ and Ca2+ in excitatory influx, the very low Na+, Ca2+ and Mg2+ concentrations of endolymph, stereocilia structure of hair cells and some proteins involved in mechanosensory signal transduction with ...
H, Gagov, M, Chichova, M, Mladenov
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FM1-43 reveals membrane recycling in adult inner hair cells of the mammalian cochlea [PDF]
, 2002 Neural transmission of complex sounds demands fast and sustained rates of synaptic release from the primary cochlear receptors, the inner hair cells (IHCs). The cells therefore require efficient membrane recycling.
Ashmore, JF +2 more
core +1 more source
Journal of Otology, 2020 Objectives: To evaluate the pathological changes in the blood-perilymph, blood-endolymph, and blood-nerve barriers of a patient with idiopathic sudden sensorineural hearing loss (SSNHL).
Jing Zou
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Otorhinolaryngology and Facial Plastic Surgery, 2022 Background: Noise-induced hearing loss (NIHL) is caused by chronic exposure to high-intensity sound. Although noise hazard has been extensively studied in the past decades, cochlear implants and hearing aids are only safe and clinically effective ...
Somayeh Niknazar +2 more
doaj +1 more source
Electrogenic transport and K(+) ion channel expression by the human endolymphatic sac epithelium. [PDF]
, 2015 The endolymphatic sac (ES) is a cystic organ that is a part of the inner ear and is connected to the cochlea and vestibule. The ES is thought to be involved in inner ear ion homeostasis and fluid volume regulation for the maintenance of hearing and ...
Choi, Jae Young +8 more
core +2 more sources
Imaging extracellular calcium in endolymph [PDF]
AIP Conference Proceedings, 2018 Hair cell mechanoelectrical transduction and adaptation are believed to be regulated by extracellular calcium.
C. Elliott Strimbu, Anders Fridberger
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In vivo genetic manipulation of inner ear connexin expression by bovine adeno-Associated viral vectors [PDF]
, 2017 We have previously shown that in vitro transduction with bovine adeno-associated viral (BAAV) vectors restores connexin expression and rescues gap junction coupling in cochlear organotypic cultures from connexin-deficient mice that are models DFNB1 ...
Campioni, Matteo +7 more
core +1 more source
Three-Dimensional Volumetric Measurement of Endolymphatic Hydrops in Meniere's Disease
Frontiers in Neurology, 2021 Objective: We used volumetric three-dimensional (3D) analysis to quantitatively evaluate the extent of endolymphatic hydrops (EH) in the entire inner ear.
Tae-Soo Noh +6 more
doaj +1 more source
Low Endolymph Calcium Concentrations in deafwaddler2J Mice Suggest that PMCA2 Contributes to Endolymph Calcium Maintenance [PDF]
Journal of the Association for Research in Otolaryngology, 2004 In vertebrates, transduction of sound into an electrochemical signal is carried out by hair cells that rely on calcium to perform specialized functions. The apical surfaces of hair cells are surrounded by endolymphatic fluid containing calcium at concentrations that must be maintained by active transport. The mechanism of this transport is unknown, but
J David, Wood +4 more
openaire +2 more sources