Results 51 to 60 of about 5,041 (178)

Variants encoding a restricted carboxy-terminal domain of SLC12A2 cause hereditary hearing loss in humans.

open access: yesPLoS Genetics, 2020
Hereditary hearing loss is challenging to diagnose because of the heterogeneity of the causative genes. Further, some genes involved in hereditary hearing loss have yet to be identified.
Hideki Mutai   +12 more
doaj   +1 more source

The Auditory Nerve Overlapped Waveform (ANOW) Detects Small Endolymphatic Manipulations That May Go Undetected by Conventional Measurements

open access: yesFrontiers in Neuroscience, 2017
Electrocochleography (ECochG) has been used to assess Ménière's disease, a pathology associated with endolymphatic hydrops and low-frequency sensorineural hearing loss. However, the current ECochG techniques are limited for use at high-frequencies only (≥
Jeffery T. Lichtenhan   +4 more
doaj   +1 more source

Imaging extracellular calcium in endolymph [PDF]

open access: yesAIP Conference Proceedings, 2018
Hair cell mechanoelectrical transduction and adaptation are believed to be regulated by extracellular calcium.
C. Elliott Strimbu, Anders Fridberger
openaire   +1 more source

Advances in the Treatment of Sensorineural Hearing Loss: From Traditional Therapies to Stem Cell and Gene Therapies

open access: yesAdvanced Sensor Research, Volume 5, Issue 4, April 2026.
Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen   +3 more
wiley   +1 more source

A Simulation Study of Low-Intensity Focused Ultrasound for Modulating Rotational Sense Through Acoustic Streaming in Semicircular Canal: A Pilot Study

open access: yesApplied Sciences
This study explores the feasibility of using low-intensity focused ultrasound (LIFU) to induce rotational sensations in the human semicircular canal (SCC) through the acoustic streaming effect.
Sion Cha, Wooksung Kim
doaj   +1 more source

Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies

open access: yesAnimal Models and Experimental Medicine, Volume 9, Issue 4, Page 712-734, April 2026.
This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang   +4 more
wiley   +1 more source

Computing Endolymph Hydrodynamics During Head Impulse Test on Normal and Hydropic Vestibular Labyrinth Models

open access: yesFrontiers in Neurology, 2020
Hypothesis: Build a biologic geometry based computational model to test the hypothesis that, in some circumstances, endolymphatic hydrops can mechanically cause enhanced eye velocity responses during clinical conditions of the head impulse test ...
Jorge Rey-Martinez   +4 more
doaj   +1 more source

Early synapsids neurosensory diversity revealed by CT and synchrotron scanning

open access: yesThe Anatomical Record, Volume 309, Issue 4, Page 912-929, April 2026.
Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit   +6 more
wiley   +1 more source

Hearing Preservation After Segmental Semicircular Canal Destruction: A Report of Two Rare Cases

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Semicircular canal fistulas are a complication of cholesteatomatous otitis media. In extremely rare cases, extensive destruction of the bony labyrinth may result in loss of approximately one‐third of the semicircular canal arc, often with wide exposure and partial injury to the membranous labyrinth, thereby increasing the risk of profound ...
Toru Miwa   +6 more
wiley   +1 more source

Automated volumetric analysis of the inner ear fluid space from hydrops magnetic resonance imaging using 3D neural networks

open access: yesScientific Reports
Due to the development of magnetic resonance (MR) imaging processing technology, image-based identification of endolymphatic hydrops (EH) has played an important role in understanding inner ear illnesses, such as Meniere’s disease or fluctuating ...
Tae-Woong Yoo   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy