Results 51 to 60 of about 5,024 (177)
Advanced Sensor Research, Volume 5, Issue 4, April 2026.Sensorineural hearing loss (SNHL) occurs in 1.5 billion globally, primary driven by damage of cochlear hair cells and spiral ganglion neurons. This review systematically examines current therapeutic strategies for sensorineural hearing loss, including traditional drug and physical therapies as well as emerging stem cell and gene therapies, providing a ...
Ruirui Chen +3 more
wiley +1 more source
Frontiers in Neuroscience, 2017 Electrocochleography (ECochG) has been used to assess Ménière's disease, a pathology associated with endolymphatic hydrops and low-frequency sensorineural hearing loss. However, the current ECochG techniques are limited for use at high-frequencies only (≥
Jeffery T. Lichtenhan +4 more
doaj +1 more source
Cancer therapy‐induced ototoxicity: Current challenges and emerging management strategies
Animal Models and Experimental Medicine, Volume 9, Issue 4, Page 712-734, April 2026.This review comprehensively examines the key risk factors for cancer therapy‐induced ototoxicity, including cumulative drug dose, genetic susceptibility, and combined treatment regimens. It highlights current challenges in ototoxicity monitoring, such as insufficient timeliness and limited clinical adoption, and advocates for standardized auditory ...
Yuqi Huang +4 more
wiley +1 more source
Early synapsids neurosensory diversity revealed by CT and synchrotron scanning
The Anatomical Record, Volume 309, Issue 4, Page 912-929, April 2026.Abstract Non‐mammaliaform synapsids (NMS) represent the closest relatives of today's mammals among the early amniotes. Exploring their brain and nervous system is key to understanding how mammals evolved. Here, using CT and Synchrotron scanning, we document for the first time three extreme cases of neurosensory and behavioral adaptations that probe ...
J. Benoit +6 more
wiley +1 more source
Applied SciencesThis study explores the feasibility of using low-intensity focused ultrasound (LIFU) to induce rotational sensations in the human semicircular canal (SCC) through the acoustic streaming effect.
Sion Cha, Wooksung Kim
doaj +1 more source
Hearing Preservation After Segmental Semicircular Canal Destruction: A Report of Two Rare Cases
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Semicircular canal fistulas are a complication of cholesteatomatous otitis media. In extremely rare cases, extensive destruction of the bony labyrinth may result in loss of approximately one‐third of the semicircular canal arc, often with wide exposure and partial injury to the membranous labyrinth, thereby increasing the risk of profound ...
Toru Miwa +6 more
wiley +1 more source
Frontiers in Neurology, 2020 Hypothesis: Build a biologic geometry based computational model to test the hypothesis that, in some circumstances, endolymphatic hydrops can mechanically cause enhanced eye velocity responses during clinical conditions of the head impulse test ...
Jorge Rey-Martinez +4 more
doaj +1 more source
Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Clinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 846-858, April 2026.Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
Long‐Term Outcomes in Children With Congenital Cytomegalovirus Infection
Laryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.ABSTRACT Objectives We aimed to evaluate the long‐term auditory outcomes of early antiviral therapy with valganciclovir (VGCV) in children with congenital cytomegalovirus (cCMV) infection, regardless of initial symptomatology. Methods This retrospective cohort study included 56 pediatric patients (112 ears) diagnosed with cCMV infection between 2004 ...
Noriko Morimoto +4 more
wiley +1 more source
Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere’s Disease
Frontiers in Immunology, 2017 Meniere’s disease (MD) is a rare disorder characterized by episodic vertigo, sensorineural hearing loss, tinnitus, and aural fullness. It is associated with a fluid imbalance between the secretion of endolymph in the cochlear duct and its reabsorption ...
Lidia Frejo +27 more
doaj +1 more source