Results 31 to 40 of about 5,041 (178)
Frontiers in Neurology, 2023 A perilymphatic fistula (PLF) presents with abnormal traffic in the otic capsule, causing cochlear and vestibular symptoms. However, the mechanisms underlying symptom recurrence remain controversial. Herein, we report the case of a 27-year-old female who
Yusuke Ito +5 more
doaj +1 more source
Endolymph Composition: Paradigm or Inevitability?
Physiological Research, 2018 This review is focused on the unusual composition of the endolymph of the inner ear and its function in mechanoelectrical transduction. The role of K+ and Ca2+ in excitatory influx, the very low Na+, Ca2+ and Mg2+ concentrations of endolymph, stereocilia structure of hair cells and some proteins involved in mechanosensory signal transduction with ...
H, Gagov, M, Chichova, M, Mladenov
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Statistical shape modeling of the human inner ear through micro‐computed tomography imaging
The Anatomical Record, EarlyView.In this study, 54 cadaveric temporal bone specimens underwent high‐resolution micro‐CT imaging. Images were semi‐automatically segmented and converted to 3D surface mesh models for morphological measurement and analysis. Statistical shape models were created for the inner ear, cochlea, and vestibular system, as well as for sex‐ and side‐based subgroups.
Carmine Spedaliere +8 more
wiley +1 more source
Single-cell RNA-sequencing of stria vascularis cells in the adult Slc26a4 -/- mouse
BMC Medical Genomics, 2023 Background The primary pathological alterations of Pendred syndrome are endolymphatic pH acidification and luminal enlargement of the inner ear. However, the molecular contributions of specific cell types remain poorly characterized.
Jin-Young Koh +8 more
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Slow‐Phase Nystagmus Velocity as a Risk Factor for Lateral Canal BPPV Recurrence
The Laryngoscope, EarlyView.This study investigated slow‐phase nystagmus velocity (SPV) at initial diagnosis as an objective vestibular predictor for the recurrence of lateral semicircular canal benign paroxysmal positional vertigo (BPPV). Binomial logistic regression analysis demonstrated that an elevated initial SPV is a novel, independent risk factor for recurrence ...
Chung Yoh Kim, Woo Jin Kim
wiley +1 more source
Fish and Fisheries, EarlyView.ABSTRACT Ocean acidification (OA) remains a major and underexplored threat to marine fishes, particularly regarding reproductive physiology and early life stages (ELS). Although research over the past 15 years has documented diverse OA effects, substantial knowledge gaps persist.
Rebecca J. Bridge +3 more
wiley +1 more source
Menière's Disease and Disorders of the Carbohydrate Metabolism Involving the Inner Ear
International Archives of Otorhinolaryngology, 2019 Introduction Menière’s disease was described in 1861, but there are still uncertainties regarding its pathophysiology and treatment. Endolymphatic hydrops is recognized as a fundamental pathological characteristic of the disease, as a result of an ...
Pedro L. Mangabeira Albernaz
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The Anatomical Record, Volume 309, Issue 9, Page 2315-2330, September 2026.Abstract The complex evolutionary history behind modern mammalian chewing performance and hearing function is a result of several changes in the entire skeletomuscular system of the skull and lower jaw. Lately, exciting multifunctional 3D analytical methods and kinematic simulations of feeding functions in both modern and fossil mammals and their ...
Julia A. Schultz
wiley +1 more source
Labyrinthine Abnormalities on MRI in Untreated Otosclerosis: Prevalence and Clinical Relevance
The Laryngoscope, Volume 136, Issue 8, Page 3559-3568, August 2026.In untreated otosclerosis with labyrinthine symptoms, delayed 3D FLAIR MRI rarely demonstrates endolymphatic hydrops but frequently reveals blood–labyrinth barrier (BLB) disruption. BLB enhancement is spatially associated with cochlear endosteal and round window involvement and increases with the severity of the hearing loss phenotype.
Héléna Pencroffi +7 more
wiley +1 more source
Low Endolymph Calcium Concentrations in deafwaddler2J Mice Suggest that PMCA2 Contributes to Endolymph Calcium Maintenance [PDF]
Journal of the Association for Research in Otolaryngology, 2004 In vertebrates, transduction of sound into an electrochemical signal is carried out by hair cells that rely on calcium to perform specialized functions. The apical surfaces of hair cells are surrounded by endolymphatic fluid containing calcium at concentrations that must be maintained by active transport. The mechanism of this transport is unknown, but
J David, Wood +4 more
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