Results 41 to 50 of about 5,041 (178)
Audiovestibular Outcomes After Parathyroidectomy in Primary Hyperparathyroidism
Laryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.ABSTRACT Objective To prospectively evaluate audiovestibular outcomes following parathyroidectomy in patients with primary hyperparathyroidism (pHPT) using a comprehensive battery of audiological, vestibular, and patient‐reported outcome measures. Methods This prospective observational study included 31 adult patients undergoing parathyroidectomy for ...
Erdem Köroğlu +3 more
wiley +1 more source
PLoS ONE, 2013 Slc26a4 (Δ/Δ) mice are deaf, develop an enlarged membranous labyrinth, and thereby largely resemble the human phenotype where mutations of SLC26A4 cause an enlarged vestibular aqueduct and sensorineural hearing loss.
Xiangming Li +3 more
doaj +1 more source
Advanced Science, Volume 13, Issue 39, 13 July 2026.This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang +16 more
wiley +1 more source
Disrupted Vestibular Nuclei Neuron Development in a Chick Model for Congenital Vestibular Disorders
Developmental Neurobiology, Volume 86, Issue 3, July 2026.ABSTRACT Children with syndromic, congenital vestibular disorders (CVDs) form a sac‐like inner ear with missing or truncated semicircular canals and experience delayed motor development with lifelong challenges to maintain posture and balance. How the abnormal inner ear affects downstream central vestibular neural circuitry has not been investigated ...
Elizabeth B. Bogin +5 more
wiley +1 more source
Study the biomechanical performance of the membranous semicircular canal based on bionic models
Heliyon, 2022 A BA (bionic ampulla) was designed and fabricated using an SMPF (Symmetric electrodes Metal core PVDF Fiber) sensor, which could imitate the sensory hair cells to sense the deformation of the cupula of the BA. Based on the BA, a bionic semicircular canal
Yixiang Bian +7 more
doaj +1 more source
Intraspecific variation of cochlear morphology in bowhead and beluga whales
The Anatomical Record, Volume 309, Issue 6, Page 1514-1529, June 2026.Abstract The bony labyrinth of the petrosal bone, a distinctive feature of mammal skulls, is often identified in micro‐computed tomography imaging to infer species' physiological and ecological traits. When done as part of a comparative study, one individual specimen is normally considered representative of a species, and intraspecific variation is ...
John Peacock, J. G. M. Thewissen
wiley +1 more source
β-trace protein (prostaglandin D synthase) - a stable and reliable protein in perilymph
GMS German Medical Science, 2005 Objective: Beta-trace protein (β-TP) has been analysed in human cerebrospinal fluid (CSF) and other body fluids. Beta-trace protein is a very sensitive and specific clinical marker and can confirm reliably the presence of CSF in patients with a suspected
Nekic, Marko +3 more
doaj
Jervell and Lange‐Nielsen Syndrome Related Clinical Genetics and Experimental Models
Pediatric Discovery, Volume 4, Issue 2, June 2026.ABSTRACT Jervell and Lange‐Nielsen syndrome (JLNS) is defined by electrocardiographic QT prolongation and sensorineural hearing loss, caused by homozygous or compound heterozygous variants in KCNQ1 and/or KCNE1. KCNQ1 encodes the alpha subunit Kv7.1 of the ion channels accountable for slow delayed rectifier potassium currents (IKs), whereas KCNE1 ...
Yafei Zhou +3 more
wiley +1 more source
Neural Regeneration Research, 2018 Previous animal studies have shown that stromal cell-derived factor-1 (SDF-1)/CXC chemokine receptor-4 (CXCR4) signaling pathway plays an important role in the targeted migration of bone marrow-derived mesenchymal stem cells (BMSCs) to the injured area ...
Ali Asghar Peyvandi +6 more
doaj +1 more source
Progress On Sensorineural Hearing Loss: Mechanisms and Therapies
Sensory Neuroscience, Volume 2, Issue 2, June 2026.ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang +9 more
wiley +1 more source