Results 91 to 100 of about 10,232 (247)

Effect of High‐Pressure Processing Operating Parameters on Microbial Inactivation and Bioactive Protein Preservation in Bovine Milk: A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT In the U.S., bovine milk is processed using thermal pasteurization to ensure microbial safety. However, this process alters the structure of heat‐sensitive bioactive proteins associated with the functional benefits of raw milk, including antimicrobial, immunomodulatory, and antioxidant proteins.
Rudy Sykora, Caleb Mark, Marie Biondi Ryan, Bishal Barman, Michael Pitino, David C. Dallas   +5 more
wiley   +1 more source

Antibacterial synergy between a phage endolysin and citric acid against the Gram-negative kiwifruit pathogen Pseudomonas syringae pv. actinidiae

Applied and Environmental Microbiology
Horticultural diseases caused by bacterial pathogens provide an obstacle to crop production globally. Management of the infection of kiwifruit by the Gram-negative phytopathogen Pseudomonas syringae pv.
Hazel M. Sisson, Robert D. Fagerlund, Simon A. Jackson, Y. Briers, Suzanne L. Warring, Peter C. Fineran   +5 more
semanticscholar   +1 more source

Bacteriophage and endolysin engineering for biocontrol of food pathogens/pathogens in the food: recent advances and future trends

Critical reviews in food science and nutrition, 2022
Despite advances in modern technologies, various foodborne outbreaks have continuously threatened the food safety. The overuse of and abuse/misuse of antibiotics have escalated this threat due to the prevalence of multidrug-resistant (MDR) pathogens ...
Chanyoung Lee, Hyeongsoon Kim, S. Ryu
semanticscholar   +1 more source

Prophage-triggered membrane vesicle formation through peptidoglycan damage in Bacillus subtilis [PDF]

, 2017
Bacteria release membrane vesicles (MVs) that play important roles in various biological processes. However, the mechanisms of MV formation in Gram-positive bacteria are unclear, as these cells possess a single cytoplasmic membrane that is surrounded by ...
Cárcamo-Oyarce Gerardo, Eberl Leo, Eisenstein Fabian, Gademann Karl, Hsiao Chien-Chi, Kurosawa Masaharu, Nomura Nobuhiko, Pilhofer Martin, Toyofuku Masanori, Yamamoto Tatsuya, 豊福 雅典, 野村 暢彦   +11 more
core   +1 more source

A bacteriophage endolysin that eliminates intracellular streptococci

eLife, 2016
PlyC, a bacteriophage-encoded endolysin, lyses Streptococcus pyogenes (Spy) on contact. Here, we demonstrate that PlyC is a potent agent for controlling intracellular Spy that often underlies refractory infections. We show that the PlyC holoenzyme, mediated by its PlyCB subunit, crosses epithelial cell membranes and clears intracellular Spy in a dose ...
Yang Shen, Marilia Barros, Tarek Vennemann, D Travis Gallagher, Yizhou Yin, Sara B Linden, Ryan D Heselpoth, Dennis J Spencer, David M Donovan, John Moult, Vincent A Fischetti, Frank Heinrich, Mathias Lösche, Daniel C Nelson   +13 more
openaire   +3 more sources

A comprehensive review of the applications of bacteriophage-derived endolysins for foodborne bacterial pathogens and food safety: recent advances, challenges, and future perspective

Frontiers in Microbiology, 2023
Foodborne diseases are caused by food contaminated by pathogenic bacteria such as Escherichia coli, Salmonella, Staphylococcus aureus, Listeria monocytogenes, Campylobacter, and Clostridium, a critical threat to human health.
Fazal Mehmood Khan, Fazal Mehmood Khan, Fazal Mehmood Khan, Jie-Hua Chen, Jie-Hua Chen, Rui Zhang, Bin Liu, Bin Liu   +7 more
doaj   +1 more source

An intramolecular cross-talk in D29 mycobacteriophage endolysin governs the lytic cycle and phage-host population dynamics

Science Advances
D29 mycobacteriophage encodes LysA endolysin, which mediates mycobacterial host cell lysis by targeting its peptidoglycan layer, thus projecting itself as a potential therapeutic.
Gokul Nair, V. Jain
semanticscholar   +1 more source

Regulation of a Phage Endolysin by Disulfide Caging [PDF]

Journal of Bacteriology, 2010
ABSTRACT In contrast to canonical phage endolysins, which require holin-mediated disruption of the membrane to gain access to attack the cell wall, signal anchor release (SAR) endolysins are secreted by the host sec system, where they accumulate in an inactive form tethered to the membrane by their N ...
Gabriel F, Kuty, Min, Xu, Douglas K, Struck, Elizabeth J, Summer, Ry, Young   +4 more
openaire   +2 more sources

Phage‐Host Interactions in Flavobacterium Pathogens and the Potential of Phage‐Based Disease Control in Salmonid Aquaculture

Reviews in Aquaculture, Volume 18, Issue 1, January 2026.
ABSTRACT A major bottleneck to the projected expansion of the aquaculture industry is disease outbreaks caused by bacterial pathogens. Fish diseases caused by Flavobacterium pathogens are persistent in salmonid aquaculture, and treatment is limited to antimicrobials, which contaminate the aquatic environment and promote antimicrobial resistance ...
Lotta A. I. Landor, Valeria Ruffo, Lotta‐Riina Sundberg, Lone Madsen, Mathias Middelboe   +4 more
wiley   +1 more source

EXTRACTION, PURIFICATION AND THERAPEUTIC USE OF BACTERIOPHAGE ENDOLYSIN AGAINST MULTI-DRUG RESISTANT PSEUDOMONAS AERUGINOSA: AN IN-VITRO AND IN-VIVO STUDY

The Iraqi Journal of Medical Sciences, 2018
Background: Persistent infection with multidrug resistant Pseudomonas aeruginosa (P. aeruginosa) represents a real problem for health care providers.
Mohammed Ali, Shurooq Kadhim, Ahmed Abdulamir   +2 more
doaj   +1 more source