Results 11 to 20 of about 64,056 (293)

Activity of Vsr endonucleases encoded by Neisseria gonorrhoeae FA1090 is influenced by MutL and MutS proteins

BMC Microbiology, 2018
Background The functioning of DNA repair systems is based on correct interactions between proteins involved in DNA repair. Very Short Patch (VSP) repair is a DNA repair system that corrects mismatches resulting from the deamination of 5-methylcytosine ...
Monika Adamczyk-Popławska, Katarzyna Bandyra, Agnieszka Kwiatek   +2 more
doaj   +2 more sources

Fitness effects of CRISPR endonucleases in Drosophila melanogaster populations

eLife, 2022
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 provides a highly efficient and flexible genome editing technology with numerous potential applications ranging from gene therapy to population control.
Anna M Langmüller, Jackson Champer, Sandra Lapinska, Lin Xie, Matthew Metzloff, Samuel E Champer, Jingxian Liu, Yineng Xu, Jie Du, Andrew G Clark, Philipp W Messer   +10 more
doaj   +2 more sources

Small molecule inhibitors of RNA guided endonucleases [PDF]

, 2021
The present invention relates to the use of compounds of formula (I) as inhibitors of RNA guided endonucleases, e.g., Cas9 and Cpfl, and methods for the inhibition of the function of such RNA guided endonucleases, including their use in the treatment and
Liu, Bin, Dömling, Alexander, Haisma, Hidde; id_orcid   +2 more
core   +4 more sources

Rolling Circle Enhanced Detection of Specific Restriction Endonuclease Activities in Crude Cell Extracts

Sensors, 2022
Restriction endonucleases are expressed in all bacteria investigated so far and play an essential role for the bacterial defense against viral infections.
Kamilla Vandsø Petersen, Cinzia Tesauro, Marianne Smedegaard Hede, Camilla Pages, Lærke Bay Marcussen, Josephine Geertsen Keller, Magnus Bugge, Kasper Holm, Lotte Bjergbæk, Magnus Stougaard, Christian Wejse, Birgitta R. Knudsen   +11 more
doaj   +1 more source

Crystal structures of Lymphocytic choriomeningitis virus endonuclease domain complexed with diketo-acid ligands

IUCrJ, 2018
The Arenaviridae family, together with the Bunyaviridae and Orthomyxoviridae families, is one of the three negative-stranded RNA viral families that encode an endonuclease in their genome.
Magali Saez-Ayala, Elsie Laban Yekwa, Mauro Carcelli, Bruno Canard, Karine Alvarez, François Ferron   +5 more
doaj   +1 more source

Isolation, cloning and molecular characterization of genes encoding single-strand specific endonucleases from Parsley (Petroselinum crispum L.) [PDF]

مجله بیوتکنولوژی کشاورزی, 2015
Single-strand specific (sss) nucleases (S1/P1 family) are widely used in molecular genetics studies. The most widely used sss-nucleases are those plant endonucleases with the ability of specific cleavage of mismatch loops in heteroduplex DNA molecules ...
Mahdiyeh Mirzaei, Jafar Zol Ala, Anahit Shalouzad   +2 more
doaj   +1 more source

Variabilidade genética na região its do rDNA de isolados de trichoderma spp. (Biocontrolador) e Fusarium oxysporum f. sp. Chrysanthemi Genetic variability in rDNA ITS region of Trichoderma spp. (biocontrole agent) and Fusarium oxysporum f. sp. chrysanthemi isolates

Ciência e Agrotecnologia, 2010
A análise de características morfológicas e culturais podem não ser suficientes para uma caracterização precisa das espécies de Trichoderma e Fusarium.
Josiane Pacheco Menezes, Manoeli Lupatini, Zaida Inês Antoniolli, Elena Blume, Emanuele Junges, Clarice G. Manzoni   +5 more
doaj   +1 more source

Historical Aspects of Restriction Endonucleases as Intelligent Scissors for Genetic Engineering

Fermentation, 2023
Restriction endonucleases are a component of restriction–modification systems, where the main biological function is to protect bacterial cells from incoming foreign DNA molecules.
Irina V. Alekseeva, Nikita A. Kuznetsov
doaj   +1 more source

Characterization of immobilized biomass by amplified rDNA restriction analysis (ARDRA) in an anaerobic sequencing-batch biofilm reactor (ASBBR) for the treatment of industrial wastewater

Brazilian Archives of Biology and Technology, 2012
The performance of an anaerobic sequencing-batch biofilm reactor (ASBBR- laboratory scale- 14L )containing biomass immobilized on coal was evaluated for the removal of elevated concentrations of sulfate (between 200 and 3,000 mg SO4-2·L-1) from ...
Arnaldo Sarti, Eloisa Pozzi, Marcelo Zaiat   +2 more
doaj   +1 more source

Pre-Ribosomal RNA Processing in Human Cells: From Mechanisms to Congenital Diseases

Biomolecules, 2018
Ribosomal RNAs, the most abundant cellular RNA species, have evolved as the structural scaffold and the catalytic center of protein synthesis in every living organism.
Maxime Aubert, Marie-Françoise O’Donohue, Simon Lebaron, Pierre-Emmanuel Gleizes   +3 more
doaj   +1 more source