Results 21 to 30 of about 64,056 (293)
Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BmoI. [PDF]
PLoS ONE, 2011 Homing endonucleases are site-specific DNA endonucleases that function as mobile genetic elements by introducing double-strand breaks or nicks at defined locations.
Benjamin P Kleinstiver +3 more
doaj +1 more source
Enzymatic cleavage of type II restriction endonucleases on the 2'-O-methyl nucleotide and phosphorothioate substituted DNA. [PDF]
PLoS ONE, 2013 The effects of nucleotide analogue substitution on the cleavage efficiencies of type II restriction endonucleases have been investigated. Six restriction endonucleases (EcoRV, SpeI, XbaI, XhoI, PstI and SphI) were investigated respectively regarding ...
Guojie Zhao +5 more
doaj +1 more source
Selfish DNA: Homing Endonucleases Find a Home [PDF]
, 2009 SummarySelf-splicing group I introns come in two flavours — those with a homing endonuclease to promote mobility of the intron, and those without an endonuclease.
Edgell, David R.
core +1 more source
New Insights Into DNA Repair Revealed by NucS Endonucleases From Hyperthermophilic Archaea
Frontiers in Microbiology, 2020 Hyperthermophilic Archaea (HA) thrive in high temperature environments and their genome is facing severe stability challenge due to the increased DNA damage levels caused by high temperature.
Likui Zhang +5 more
doaj +1 more source
Viruses, 2023 Nucleases are ubiquitous hydrolytic enzymes that cleave phosphodiester bond of DNA (DNases), RNA (RNases), or protein-RNA/DNA (phosphodiesterases), within the strand (endonucleases) or from the end (exonucleases) [...]
Zhengqiang Wang, Robert J. Geraghty
doaj +1 more source
Mobile DNA elements in T4 and related phages
Virology Journal, 2010 Mobile genetic elements are common inhabitants of virtually every genome where they can exert profound influences on genome structure and function in addition to promoting their own spread within and between genomes.
Belfort Marlene +2 more
doaj +1 more source
Molecular cloning and physical mapping of murine cytomegalovirus DNA [PDF]
, 1983 Murine cytomegalovirus (MCMV) Smith strain DNA is cleaved by restriction endonuclease HindIII into 16 fragments, ranging in size from 0.64 to 22.25 megadaltons.
Ebeling, Angelika +3 more
core +1 more source
Endonuclease activity in lipocalins [PDF]
Biochemical Journal, 2000 Several lipocalins contain conserved amino acid sequences similar to the phosphodiester bond cleavage domain of sugar non-specific magnesium-dependent nucleases of the Serratia marcescens type. His-89 and Glu-127 of the S. marcescens endonuclease are believed to have a role in the active catalytic site by the attack of a water molecule at the ...
T N, Yusifov +3 more
openaire +2 more sources
Restriction endonucleases from Bifidobacterium bifidum [PDF]
, 1984 Three restriction endonucleases, BbiI, BbiII and BbiIII, have been isolated from Bifidobacterium bifidum. The recognition and cleavage specificity of BbiII was determined to be 5'-GR↓CGYC-3', identical to that of AcyI isolated from a cyanobacterium ...
Kiwaki, Mayumi +3 more
core +1 more source
Genes and Environment, 2017 Apurinic/apyrimidinic (AP) sites are one of the most frequent DNA lesions. AP sites inhibit transcription and DNA replication, and induce cell death. AP endonucleases are key enzymes in AP site repair. Several types of AP endonucleases have been reported,
Masafumi Funakoshi +3 more
doaj +1 more source