Results 211 to 220 of about 155,310 (382)

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

open access: yesThe FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola   +11 more
wiley   +1 more source

Widespread and intron-rich mirusviruses are predicted to reproduce in nuclei of unicellular eukaryotes. [PDF]

open access: yesNat Microbiol
Medvedeva S   +11 more
europepmc   +1 more source

Bacterial persistence by RNA endonucleases

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2011
Etienne Maisonneuve   +3 more
semanticscholar   +1 more source

A comprehensive overview of yeast libraries and their role in advancing cell biology

open access: yesThe FEBS Journal, EarlyView.
Systematic, genome‐wide yeast mutant libraries have revolutionized systems and cell biology. By allowing high‐throughput interrogation of every gene and protein, they have defined gene essentiality, charted protein localization, illuminated function, mapped interactions, and more.
Din Baruch, Maya Schuldiner, Ofir Klein
wiley   +1 more source

Stimulation of Human Endonuclease III by Y Box-binding Protein 1 (DNA-binding Protein B) [PDF]

open access: hybrid, 2001
Dina R. Marenstein   +7 more
openalex   +1 more source

Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma

open access: yesThe FEBS Journal, EarlyView.
Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris   +2 more
wiley   +1 more source

A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors

open access: yesInternational Journal of Cosmetic Science, EarlyView.
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin   +7 more
wiley   +1 more source

Generation of ρ 0 cells utilizing a mitochondrially targeted restriction endonuclease and comparative analyses [PDF]

open access: gold, 2008
Alexandra Kukat   +7 more
openalex   +1 more source

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