Results 61 to 70 of about 64,056 (293)
Cloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L. [PDF]
PLoS ONE, 2014 Apurinic/apyrimidinic (AP) endonucleases are key DNA repair enzymes involved in the base excision repair (BER) pathway. In BER, an AP endonuclease cleaves DNA at AP sites and 3'-blocking moieties generated by DNA glycosylases and/or oxidative damage.
Botagoz Joldybayeva +7 more
doaj +1 more source
The inhibition of restriction endonucleases due to Z-DNA in negatively supercoiled plasmid [PDF]
, 1991 Plasmid pGC20 containing the (dGC)??? insert in Sma1 recognition site has been used to study the inhibition of cleavage by different restriction endonucleases due to Z-DNA formation in (dCG)b10 sequence of the negatively supercoiled plasmid.
Zh.A. Bes'chetnikova +7 more
core +1 more source
Advanced Science, EarlyView.Chromosome 16q loss drives genomic instability through disruption of the CYLD–TIRR–53BP1 axis. CYLD preserves homologous recombination by stabilizing TIRR and limiting 53BP1 accumulation at DNA double‐strand breaks. CYLD deficiency redirects repair toward error‐prone non‐homologous end joining, promotes mutational burden and homologous recombination ...
Mingming Lu +14 more
wiley +1 more source
Two restriction endonucleases [PDF]
Biochemistry and Molecular Biology Education, 2006 AbstractTerms to be familiar with before you start to solve the test: restriction endonucleases; palindromic sequences; blunt ends; cohesive (“sticky”) ends; in vitro DNA synthesis; radioactive nucleotide precursors; template‐primer complexes; DNA ligation.
openaire +2 more sources
Type II restriction endonucleases: Structure and mechanism
, 2005 Type II restriction endonucleases are components of restriction modification systems that protect bacteria and archaea against invading foreign DNA.
Pingoud A. +3 more
core +1 more source
Diversity of cultured isolates and field populations of the arbuscular mycorrhizal fungus "Glomus intraradices" : development and application of molecular detection methods for mitochondrial haplotypes [PDF]
, 2010 Today’s plant communities have evolved together with arbuscular mycorrhizal fungi (AMF, Glomeromycota) for millions of years. In “arbuscular mycorrhiza”, a mutualistic symbiosis, plants provide carbohydrates to the fungi, which in turn make mineral ...
Börstler, Boris
core +1 more source
Advanced Science, EarlyView.ABSTRACT Intervertebral disc degeneration (IDD) is driven by ferroptosis of nucleus pulposus cells (NPCs) as a core pathological mechanism. Nucleus pulposus progenitor cells (NPPCs), exhibiting stem cell‐like properties, yield extracellular vesicles (PEVs) with high affinity for NPCs and enable targeted phenotypic regulation.
Jing Yan +10 more
wiley +1 more source
BioTechniques, 1999 REF Select, expert system software, has been developed to assist in the selection of optimal restriction endonucleases for restriction endonuclease fingerprinting (REF), a method for rapid and sensitive mutation screening of long DNA segments (1–2 kb ...
William A. Scaringe +3 more
doaj +1 more source
Tapping natural reservoirs of homing endonucleases for targeted gene modification
, 2011 Homing endonucleases mobilize their own genes by generating double-strand breaks at individual target sites within potential host DNA. Because of their high specificity, these proteins are used for “genome editing” in higher eukaryotes.
Barry L. Stoddard +8 more
core +1 more source
Advanced Science, EarlyView.Corynoxine exerts potent broad‐spectrum anticancer activity by directly targeting NQO1. This interaction dissociates the oncogenic NQO1‐PTPA complex, releasing PTPA to robustly activate the tumor suppressor PP2A. Consequently, downstream Raf/MEK/ERK and PI3K/AKT signaling pathways are suppressed, downregulating c‐Myc and driving tumor regression ...
Guoqing Hou +6 more
wiley +1 more source