Cloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L. [PDF]
PLoS ONE, 2014 Apurinic/apyrimidinic (AP) endonucleases are key DNA repair enzymes involved in the base excision repair (BER) pathway. In BER, an AP endonuclease cleaves DNA at AP sites and 3'-blocking moieties generated by DNA glycosylases and/or oxidative damage.
Botagoz Joldybayeva +7 more
doaj +1 more source
A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes [PDF]
, 2017 A nomenclature is described for restriction endonucleases, DNA methyltransferases, homing endonucleases and related genes and gene products. It provides explicit categories for the many different Type II enzymes now identified and provides a system for ...
Belfort, Marlene +46 more
core
Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions [PDF]
, 2013 During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation.
A Chavez +115 more
core +3 more sources
Targeted Mutagenesis Using RNA-guided Endonucleases in Mosses
Bio-Protocol, 2017 RNA-guided endonucleases (RGENs) have been used for genome editing in various organisms. Here, we demonstrate a simple method for performing targeted mutagenesis and genotyping in a model moss species, Physcomitrella patens, using RGENs.
Toshihisa Nomura, Hitoshi Sakakibara
doaj +1 more source
Phylogenetic diversity of Moroccan cork oak woodlands fungi : mythe ou réalité ? [PDF]
, 2009 La variabilité interspécifique de 87 carpophores des champignons appartenant à 15 genres et 39 espèces ont été évaluées par l'analyse du polymorphisme de longueur de fragments de restriction (RFLP) de l'espaceur interne transcrit (ITS).
Abourouh, Mohamed +5 more
core
The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects. [PDF]
, 2018 Genome instability is associated with tumorigenesis. Here, we identify a role for the histone Htz1, which is deposited by the Swr1 chromatin-remodeling complex (SWR-C), in preventing genome instability in the absence of the replication fork/replication ...
Branzei, Dana +5 more
core +2 more sources
Nucleic Acids Research, 1988 Treatment of DNA containing AP sites with either T4 UV endonuclease or with E. coli endonuclease III followed by a human class II AP endonuclease releases a putative beta-elimination product. This result suggests that both the T4 endonuclease and E. coli endonuclease III class I AP endonucleases catalyze phosphodiester bond cleavage via a lyase- rather
Joon Kim, Stuart Linn
openaire +4 more sources
Characterization of endonuclease activities in Moloney murine leukemia virus and its replication-defective mutants [PDF]
, 1987 To study Moloney murine leukemia virus (M-MulV) proteins associated with the integration of proviral DNA into the host chromosome, we isolated endonuclease activities from purified virion preparations of the wild type and two of its replication mutants ...
Baltimore, David, Panet, Amos
core
Massively parallel determination and modeling of endonuclease substrate specificity [PDF]
, 2015 We describe the identification and characterization of novel homing endonucleases using genome database mining to identify putative target sites, followed by high throughput activity screening in a bacterial selection system.
Baker, David +6 more
core +1 more source
EPIGENETICS TODAY AND TOMORROW
Вавиловский журнал генетики и селекции, 2015 Epigenetics is a science of inheritable organism properties that are not associated with changes in the DNA nucleotide sequence but can be indirectly encoded in the genome. The most known epigenetic mechanisms (signals) are enzymatic DNA methylation, the
B. F. Vanyushin
doaj