Results 81 to 90 of about 106,966 (240)

Molecular Characterisation of Bacteriophage K Towards Applications for the Biocontrol of Pathogenic Staphylococci [PDF]

, 2006
End of project reportThe aim of this work was to characterise staphylococcal bacteriophage (a bacterial virus) and to assess their potential as therapeutic agents against pathogenic strains of Staphylococcus aureus, particularly mastitis-causing strains.
Coffey, Aidan, Fitzgerald, Gerald F, Flynn, James, Meaney, William J, O'Flaherty, Sarah, Ross, R Paul   +5 more
core  

Biophysical and electrochemical studies of protein-nucleic acid interactions [PDF]

, 2015
This review is devoted to biophysical and electrochemical methods used for studying protein-nucleic acid (NA) interactions. The importance of NA structure and protein-NA recognition for essential cellular processes, such as replication or transcription ...
A Abi, A Aravin, A Danhel, A Danhel, A Re, A Simonova, A Szabo, AA Gorodetsky, AA Travers, AL Feig, AM Cobb, AN Kawde, Andrew M. Cobb, B Deng, B Dey, B McConnell, BOS Scott, C Schildkraut, CA Hunter, CN N’Soukpoe-Kossi, CR Calladine, CS Yeh, D Rhodes, DB Dogini, DG Brown, DJ Richard, DK Hendrix, E Farjami, E Palecek, E Palecek, E Palecek, E Palecek, E Palecek, E Palecek, E Palecek, E Palecek, E Palecek, E Palecek, E Palecek, E Stejskalova, EB Jagelska, EB Jagelska, EJ Nam, EM Boon, EM Boon, EM Boon, FU Hartl, G Zauner, GP Yan, H Cahova, H Pivonkova, Hana Pivonkova, HF Wang, J Balintova, J Balintova, J Batra, J Coufal, J Labuda, J Majka, J Vacek, J Wang, JA McClellan, JD Puglisi, JL Wang, JL Wang, K Cahova-Kucharikova, K Nemcova, K Nemcova, K Teilum, KV Morris, L Havran, L Jen-Jacobson, LD Hansen, LL Pang, LM Hellman, Ludek Havran, M Bartosik, M Brazdova, M Brazdova, M Brenowitz, M Fojta, M Fojta, M Fojta, M Fojta, M Fojta, M Fojta, M Fojta, M Fojta, M Heyrovsky, M Hocek, M Kampmann, M Masarik, M Oda, M Willander, Miroslav Fojta, NB Leontis, NB Muren, NC Seeman, NN Salim, O Bell, P Zhang, PA Garrity, PC Weber, PH Hippel von, PH Hippel von, PJ Hagerman, R Christova, R Kaptein, RE Dickerson, Richard P. Bowater, RJ Falconer, RP Bowater, S Khezrian, S Lee, S Tan, SA Coulocheri, SE Halford, SR Holbrook, SR Rajski, T Hianik, TM Hall, TS Furey, V Brazda, V Ostatna, V Petri, V Ramakrishnan, V Vargova, W Filipowicz, WD Kohn, XB Yin, XX He, Y Xiao, Y Xiao, Y Zhang, YH Xu, Z Yang, ZS Wu   +136 more
core   +1 more source

Creation of a novel telomere-cutting endonuclease based on the EN domain of telomere-specific non-long terminal repeat retrotransposon, TRAS1

Mobile DNA, 2010
Background The ends of chromosomes, termed telomeres consist of repetitive DNA. The telomeric sequences shorten with cell division and, when telomeres are critically abbreviated, cells stop proliferating.
Yoshitake Kazutoshi, Aoyagi Hideyuki, Fujiwara Haruhiko   +2 more
doaj   +1 more source

Rapid identification and differentiation of the vaccine strain Rac H from EHV 1 field isolates using a non-radioactive DNA probe [PDF]

, 1992
A method for rapid differentiation between the EHV 1 live vaccine strain Rac H and field isolates is described. Total DNA was isolated from virus-infected small scale cell cultures.
Eichhorn, Werner, Hübert, P. H., Meyer, H., Schwend, C.   +3 more
core   +1 more source

Online High-throughput Mutagenesis Designer Using Scoring Matrix of Sequence-specific Endonucleases

Journal of Integrative Bioinformatics, 2015
CRISPR Cas9 and other sequence-specific endonucleases are fundamental genome editors supporting gene knockout and gene therapy. A speedy and accurate computational allele designer is required for a high through-put gene mutagenesis pipeline using these ...
Guo Dayong, Li Xiaojing, Zhu Pan, Feng Yanrong, Yang Juan, Zheng Zhihong, Yang Wei, Zhang Enuo, Zhou Shenglai, Wang Hongyu   +9 more
doaj   +2 more sources

DNA Binding and Degradation by the HNH Protein ColE7 [PDF]

, 2004
The bacterial toxin ColE7 bears an HNH motif which has been identified in hundreds of prokaryotic and eukaryotic endonucleases, involved in DNA homing, restriction, repair, or chromosome degradation.
Chak, Kin-Fu, Cheng, Yi-Sheng, Hsia, Kuo-Chiang, Ku, Wen-Yen, Liang, Po-Huang, Yuan, Hanna S.   +5 more
core   +1 more source

Genetic polymorphism among 14 elite Coffea arabica L. cultivars using RAPD markers associated with restriction digestion

Genetics and Molecular Biology, 2003
Knowledge of the genetic variability among genotypes is important for the transfer of useful genes and to maximize the use of available germplasm resources. This study was carried out to assess the genetic variability of 14 elite Coffea arabica cultivars
Tumoru Sera, Paulo Maurício Ruas, Claudete de Fátima Ruas, Leandro Eugênio Cardamone Diniz, Valdemar de Paula Carvalho, Leandro Rampim, Eduardo Augusto Ruas, Sheila Recepute da Silveira   +7 more
doaj   +1 more source

Selective microbial genomic DNA isolation using restriction endonucleases.

PLoS ONE, 2014
To improve the metagenomic analysis of complex microbiomes, we have repurposed restriction endonucleases as methyl specific DNA binding proteins. As an example, we use DpnI immobilized on magnetic beads.
Helen E Barnes, Guohong Liu, Christopher Q Weston, Paula King, Long K Pham, Shannon Waltz, Kimberly T Helzer, Laura Day, Dan Sphar, Robert T Yamamoto, R Allyn Forsyth   +10 more
doaj   +1 more source

The Molecular Perspective: Restriction Endonucleases [PDF]

STEM CELLS, 2002
The Oncologist 2002;7:82-83 www.TheOncologist.com We live in a remarkable age. Physicians now have an unprecedented range of options for helping their patients. Surgery and radiology are using advanced technologies to pinpoint treatments. Chemotherapeutic approaches are showing ever-greater effectiveness and specificity, approaching the goal of a ...
openaire   +4 more sources

The role of DNA restriction-modification systems in the biology of Bacillus anthracis

Frontiers in Microbiology, 2016
Restriction-modification (R-M) systems are widespread among prokaryotes and, depending on their type, may be viewed as selfish genetic elements that persist as toxin-antitoxin modules or as cellular defense systems against phage infection.
Ramakrishnan eSitaraman
doaj   +1 more source