Results 1 to 10 of about 146,431 (197)

Degradation of soybean meal proteins by wheat malt endopeptidase and the antioxidant capacity of the enzymolytic products

open access: yesFrontiers in Nutrition, 2023
This study investigated the hydrolysis effect of the endopeptidase from wheat malt on the soybean meal proteins. The results indicated that the endopeptidase broke the peptide bonds of soybean meal proteins and converted the alcohol- and alkali-soluble ...
Jingxiao Fan   +3 more
doaj   +1 more source

Evaluation of Enkephalin-Degrading Enzymes in Sperm from Heroin-Addicted Men [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2020
Background The aim of this study was to investigate two enkephalin-degrading enzymes, aminopeptidase N (APN/ CD13) and endopeptidase (NEP/CD10), gene and protein expression levels in sperm samples of fertile and heroin- addicted men, and the ...
Samira Rezaei-Mojaz   +9 more
doaj   +1 more source

Potential Activities of Freshwater Exo- and Endo-Acting Extracellular Peptidases in East Tennessee and the Pocono Mountains

open access: yesFrontiers in Microbiology, 2018
Proteins constitute a particularly bioavailable subset of organic carbon and nitrogen in aquatic environments but must be hydrolyzed by extracellular enzymes prior to being metabolized by microorganisms.
Lauren Mullen   +8 more
doaj   +1 more source

Characterization of LysBC17, a Lytic Endopeptidase from Bacillus cereus

open access: yesAntibiotics, 2019
Bacillus cereus, a Gram-positive bacterium, is an agent of food poisoning. B. cereus is closely related to Bacillus anthracis, a deadly pathogen for humans, and Bacillus thuringenesis, an insect pathogen.
Steven M. Swift   +6 more
doaj   +1 more source

Genetic Evidence for Distinct Functions of Peptidoglycan Endopeptidases in Escherichia coli

open access: yesFrontiers in Microbiology, 2020
Peptidoglycan (PG) is an essential component of the bacterial exoskeleton that plays a pivotal role in the maintenance of cell shape and resistance to cell lysis under high turgor pressures.
Si Hyoung Park   +4 more
doaj   +1 more source

TCR-Induced Tyrosine Phosphorylation at Tyr270 of SUMO Protease SENP1 by Lck Modulates SENP1 Enzyme Activity and Specificity

open access: yesFrontiers in Cell and Developmental Biology, 2022
Small ubiquitin-like modifier (SUMO) modification plays an important regulatory role in T cell receptor (TCR) signaling transduction. SUMO-specific proteases (SENPs) have dual-enzyme activities; they can both process SUMO precursors as endopeptidases and
Yun-Yi Li   +6 more
doaj   +1 more source

Crystal Structure of Bovine Alpha-Chymotrypsin in Space Group P65

open access: yesCrystals, 2018
Chymotrypsin is a protease that is commonly used as a standard for protein crystallization and as a model system for studying serine proteases. Unliganded bovine α-chymotrypsin was crystallized at neutral pH using ammonium sulphate as the precipitant ...
Andrew C. Marshall   +4 more
doaj   +1 more source

Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples

open access: yesToxins, 2015
Botulinum neurotoxins (BoNTs) cause the life-threatening neurological illness botulism in humans and animals and are divided into seven serotypes (BoNT/A–G), of which serotypes A, B, E, and F cause the disease in humans. BoNTs are classified as “category
Stéphanie Simon   +10 more
doaj   +1 more source

Computer-aided lead optimization: improved small-molecule inhibitor of the zinc endopeptidase of botulinum neurotoxin serotype A. [PDF]

open access: yesPLoS ONE, 2007
Optimization of a serotype-selective, small-molecule inhibitor of botulinum neurotoxin serotype A (BoNTA) endopeptidase is a formidable challenge because the enzyme-substrate interface is unusually large and the endopeptidase itself is a large, zinc ...
Jing Tang   +4 more
doaj   +1 more source

Serum neprilysin levels are elevated in preeclampsia

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2021
Objective: To evaluate the possible associations between serum Neprilysin (NEP) levels and preeclampsia and mild and severe preeclampsia subgroups. Materials and methods: Fifty-five consecutive women with mild preeclampsia and fifty-five consecutive ...
Nevin Tüten   +8 more
doaj   +1 more source

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